2GXA
 
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7LIU
 | | DDX3X bound to ATP analog and remodeled RNA:DNA hybrid | | Descriptor: | 5'-R(*GP*GP*GP*CP*GP*GP*G)-D(P*CP*CP*CP*GP*CP*CP*C)-3', ATP-dependent RNA helicase DDX3X, MAGNESIUM ION, ... | | Authors: | Enemark, E.J, Yu, S. | | Deposit date: | 2021-01-27 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | DDX3X bound to ATP analog and remodeled RNA:DNA hybrid
To Be Published
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1F08
 | | CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN E1 FROM PAPILLOMAVIRUS | | Descriptor: | BROMIDE ION, REPLICATION PROTEIN E1 | | Authors: | Enemark, E.J, Chen, G, Vaughn, D.E, Stenlund, A, Joshua-Tor, L. | | Deposit date: | 2000-05-15 | | Release date: | 2001-05-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus.
Mol.Cell, 6, 2000
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1KSY
 | | Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex | | Descriptor: | E1 Recognition Sequence, Strand 1, Strand 2, ... | | Authors: | Enemark, E.J, Stenlund, A, Joshua-Tor, L. | | Deposit date: | 2002-01-14 | | Release date: | 2002-03-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
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1KSX
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6MII
 | | Crystal structure of minichromosome maintenance protein MCM/DNA complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | Authors: | Enemark, E.J, Meagher, M, Epling, L.B. | | Deposit date: | 2018-09-19 | | Release date: | 2019-07-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | DNA translocation mechanism of the MCM complex and implications for replication initiation.
Nat Commun, 10, 2019
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6WNZ
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4R7Y
 | | Crystal structure of an active MCM hexamer | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Miller, J.M, Arachea, B.T, Epling, L.B, Enemark, E.J. | | Deposit date: | 2014-08-28 | | Release date: | 2014-10-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Analysis of the crystal structure of an active MCM hexamer.
Elife, 3, 2014
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1ZRO
 | | Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose | | Descriptor: | CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II | | Authors: | Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L. | | Deposit date: | 2005-05-19 | | Release date: | 2005-08-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
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5IY0
 | | PfMCM N-terminal domain double hexamer | | Descriptor: | Cell division control protein 21, ZINC ION | | Authors: | Meagher, M, Enemark, E.J. | | Deposit date: | 2016-03-23 | | Release date: | 2016-07-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of a double hexamer of the Pyrococcus furiosus minichromosome maintenance protein N-terminal domain.
Acta Crystallogr.,Sect.F, 72, 2016
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1ZRL
 | | Crystal structure of EBA-175 Region II (RII) | | Descriptor: | CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II | | Authors: | Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L. | | Deposit date: | 2005-05-19 | | Release date: | 2005-08-09 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
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4YWM
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4YWK
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4YWL
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8EAH
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 1 | | Descriptor: | 16-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.48 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAI
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 2 | | Descriptor: | 16-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAJ
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 1 | | Descriptor: | 46-mer DNA strand, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAF
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 1 | | Descriptor: | 12-mer oligo dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAL
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and DNA. Class 1. Merged particles from datasets with 3 different DNA entities | | Descriptor: | DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.34 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAG
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 2 | | Descriptor: | 12-mer oligo-dT, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAM
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and DNA. Class 2. Merged particles from datasets with 3 different DNA entities | | Descriptor: | DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.59 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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8EAK
 | | SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 2 | | Descriptor: | 46-mer DNA, MAGNESIUM ION, Minichromosome maintenance protein MCM, ... | | Authors: | Meagher, M, Myasnikov, A, Enemark, E.J. | | Deposit date: | 2022-08-29 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Int J Mol Sci, 23, 2022
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4POF
 | | PfMCM N-terminal domain without DNA | | Descriptor: | Cell division control protein 21, ZINC ION | | Authors: | Froelich, C.A, Kang, S, Epling, L.B, Bell, S.P, Enemark, E.J. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.648 Å) | | Cite: | A conserved MCM single-stranded DNA binding element is essential for replication initiation.
Elife, 3, 2014
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4POG
 | | MCM-ssDNA co-crystal structure | | Descriptor: | 30-mer oligo(dT), Cell division control protein 21, ZINC ION | | Authors: | Froelich, C.A, Kang, S, Epling, L.B, Bell, S.P, Enemark, E.J. | | Deposit date: | 2014-02-25 | | Release date: | 2014-04-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.203 Å) | | Cite: | A conserved MCM single-stranded DNA binding element is essential for replication initiation.
Elife, 3, 2014
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4PXA
 | | DEAD-box RNA helicase DDX3X Cancer-associated mutant D354V | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX3X, PHOSPHATE ION | | Authors: | Epling, L.B, Grace, C.R, Lowe, B.R, Partridge, J.F, Enemark, E.J. | | Deposit date: | 2014-03-22 | | Release date: | 2015-03-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis.
J.Mol.Biol., 427, 2015
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