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4S3N
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BU of 4s3n by Molmil
Crystal structure of human OAS3 domain I in complex with dsRNA
Descriptor: 2'-5'-oligoadenylate synthase 3, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')
Authors:Donovan, J, Whitney, G, Rath, S, Korennykh, A.
Deposit date:2015-02-26
Release date:2015-03-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3.
Proc.Natl.Acad.Sci.USA, 112, 2015
4IG8
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BU of 4ig8 by Molmil
Structural basis for cytosolic double-stranded RNA surveillance by human OAS1
Descriptor: 2'-5'-oligoadenylate synthase 1, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Donovan, J, Korennykh, A.
Deposit date:2012-12-16
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4OAV
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BU of 4oav by Molmil
Complete human RNase L in complex with 2-5A (5'-ppp heptamer), AMPPCP and RNA substrate.
Descriptor: (2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-({[(S)-hydroxy{[(2R,3S,4S)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy}phosphoryl]oxy}methyl)tetrahydrofuran-3-yl dihydrogen phosphate, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Han, Y, Donovan, J, Rath, S, Whitney, G, Chitrakar, A, Korennykh, A.
Deposit date:2014-01-06
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science, 343, 2014
4OAU
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BU of 4oau by Molmil
Complete human RNase L in complex with biological activators.
Descriptor: 2-5A-dependent ribonuclease, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Han, Y, Donovan, J, Rath, S, Whitney, G, Chitrakar, A, Korennykh, A.
Deposit date:2014-01-06
Release date:2014-03-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science, 343, 2014
4G8K
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BU of 4g8k by Molmil
Intact sensor domain of human RNase L in the inactive signaling state
Descriptor: 2-5A-dependent ribonuclease
Authors:Han, Y, Whitney, G, Donovan, J, Korennykh, A.
Deposit date:2012-07-23
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes.
Cell Rep, 2, 2012
4G8L
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BU of 4g8l by Molmil
Active state of intact sensor domain of human RNase L with 2-5A bound
Descriptor: 2-5A-dependent ribonuclease, 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE
Authors:Han, Y, Whitney, G, Donovan, J, Korennykh, A.
Deposit date:2012-07-23
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes.
Cell Rep, 2, 2012
5MO4
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BU of 5mo4 by Molmil
ABL1 kinase (T334I_D382N) in complex with asciminib and nilotinib
Descriptor: Nilotinib, Tyrosine-protein kinase ABL1, asciminib
Authors:Cowan-Jacob, S.W.
Deposit date:2016-12-13
Release date:2017-04-05
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1.
Nature, 543, 2017

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PDB entries from 2024-03-27

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