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1MPV
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BU of 1mpv by Molmil
Structure of bhpBR3, the BAFF-binding loop of BR3 embedded in a beta-hairpin peptide
Descriptor: BLyS Receptor 3
Authors:Kayagaki, N, Yan, M, Seshasayee, D, Wang, H, Lee, W, French, D.M, Grewal, I.S, Cochran, A.G, Gordon, N.C, Yin, J, Starovasnik, M.A, Dixit, V.M.
Deposit date:2002-09-12
Release date:2002-10-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.
Immunity, 17, 2002
1DGN
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BU of 1dgn by Molmil
SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION
Descriptor: ICEBERG (PROTEASE INHIBITOR)
Authors:Humke, E.W, Shriver, S.K, Starovasnik, M.A, Fairbrother, W.J, Dixit, V.M.
Deposit date:1999-11-24
Release date:2000-10-09
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:ICEBERG: a novel inhibitor of interleukin-1beta generation.
Cell(Cambridge,Mass.), 103, 2000
3U30
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BU of 3u30 by Molmil
Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin
Descriptor: Heavy chain Fab, Light chain Fab, linear di-ubiquitin
Authors:Matsumoto, M.L, Dong, K.C, Yu, C, Phu, L, Gao, X, Hannoush, R.N, Hymowitz, S.G, Kirkpatrick, D.S, Dixit, V.M, Kelley, R.F.
Deposit date:2011-10-04
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.428 Å)
Cite:Engineering and structural characterization of a linear polyubiquitin-specific antibody.
J.Mol.Biol., 418, 2012
1OSG
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BU of 1osg by Molmil
Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold
Descriptor: BR3 derived PEPTIDE, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B
Authors:Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A.
Deposit date:2003-03-19
Release date:2003-05-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, 42, 2003
1OSX
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BU of 1osx by Molmil
Solution Structure of the Extracellular Domain of BLyS Receptor 3 (BR3)
Descriptor: Tumor necrosis factor receptor superfamily member 13C
Authors:Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A.
Deposit date:2003-03-20
Release date:2003-05-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, 42, 2003
1RJ8
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BU of 1rj8 by Molmil
The crystal structure of TNF family member EDA-A2
Descriptor: ectodysplasin-A isoform EDA-A2
Authors:Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M.
Deposit date:2003-11-18
Release date:2003-12-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Crystal Structure of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity
STRUCTURE, 11, 2003
1RJ7
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BU of 1rj7 by Molmil
Crystal structure of EDA-A1
Descriptor: Ectodysplasin A
Authors:Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M.
Deposit date:2003-11-18
Release date:2003-12-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.
Structure, 11, 2003
7LW1
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BU of 7lw1 by Molmil
Human phosphofructokinase-1 liver type bound to activator NA-11
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Lynch, E.M, Kollman, J.M, Webb, B.
Deposit date:2021-02-27
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Selective activation of PFKL suppresses the phagocytic oxidative burst.
Cell, 184, 2021
3DVG
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BU of 3dvg by Molmil
Crystal structure of K63-specific fab Apu.3A8 bound to K63-linked di-ubiquitin
Descriptor: Human IgG1 fab fragment heavy chain, Human IgG1 fab fragment light chain, Ubiquitin, ...
Authors:Hymowitz, S.G.
Deposit date:2008-07-18
Release date:2008-09-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134, 2008
3DVN
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BU of 3dvn by Molmil
Crystal structure of K63-specific fab Apu2.16 bound to K63-linked di-ubiquitin
Descriptor: Human IgG1 fab fragment heavy chain, Human IgG1 fab fragment light chain, Ubiquitin, ...
Authors:Hymowitz, S.G.
Deposit date:2008-07-18
Release date:2008-09-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134, 2008
5DS8
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BU of 5ds8 by Molmil
Context-independent anti-hypusine antibody FabHpu98 in complex with hypusine
Descriptor: 1,2-ETHANEDIOL, Fab Hou98 Light Chain, Fab Hpu98 Heavy Chain, ...
Authors:Zhai, Q, Carter, P.J.
Deposit date:2015-09-17
Release date:2016-01-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
J.Mol.Biol., 428, 2016
5DTF
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BU of 5dtf by Molmil
context-independent anti-hypusine antibody FabHpu98.61 in complex with hypusine
Descriptor: 1,2-ETHANEDIOL, Fab Hpu98.61 Heavy Chain, Fab Hpu98.61 Light Chain, ...
Authors:Zhai, Q, Carter, P.J.
Deposit date:2015-09-18
Release date:2016-02-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
J.Mol.Biol., 428, 2016
5DUB
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BU of 5dub by Molmil
Context-independent anti-hypusine antibody FabHpu98 in complex with deoxyhypusine
Descriptor: 1,2-ETHANEDIOL, Fab Hpu98 Heavy chain, Fab Hpu98 Light chain, ...
Authors:Zhai, Q, Carter, P.J.
Deposit date:2015-09-18
Release date:2016-01-20
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
J.Mol.Biol., 428, 2016
5DSC
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BU of 5dsc by Molmil
Context-independent anti-hypusine antibody FabHpu24.B in complex with hypusine
Descriptor: Fab Hou24.B Light Chain, Fab Hpu24.B Heavy Chain, Peptide: GLY-HPU-GLY-SER-GLY
Authors:Zhai, Q, Carter, P.J.
Deposit date:2015-09-17
Release date:2016-01-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
J.Mol.Biol., 428, 2016
5DRN
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BU of 5drn by Molmil
Context-independent anti-hypusine antibody FabHpu24 in complex with hypusine
Descriptor: Fab Hpu24 Heavy chain, Fab Hpu24 Light chain, GLYCEROL, ...
Authors:Zhai, Q, Carter, P.J.
Deposit date:2015-09-16
Release date:2016-01-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies.
J.Mol.Biol., 428, 2016
3NOB
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BU of 3nob by Molmil
Structure of K11-linked di-ubiquitin
Descriptor: SULFATE ION, Ubiquitin
Authors:Dong, K.C, Matsumoto, M.L, Hymowitz, S.G.
Deposit date:2010-06-25
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:K11-Linked Polyubiquitination in Cell Cycle Control Revealed by a K11 Linkage-Specific Antibody.
Mol.Cell, 39, 2010
3OJ4
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BU of 3oj4 by Molmil
Crystal structure of the A20 ZnF4, ubiquitin and UbcH5A complex
Descriptor: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, Ubiquitin-conjugating enzyme E2 D1, ...
Authors:Bosanac, I, Hymowitz, S.G.
Deposit date:2010-08-20
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
Mol.Cell, 40, 2010
3OJ3
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BU of 3oj3 by Molmil
Crystal structure of the A20 ZnF4 and ubiquitin complex
Descriptor: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, ZINC ION
Authors:Bosanac, I, Hymowitz, S.G.
Deposit date:2010-08-20
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-KB Signaling
Mol.Cell, 40, 2010
3PTF
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BU of 3ptf by Molmil
X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin
Descriptor: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1
Authors:Bosanac, I, Hymowitz, S.G.
Deposit date:2010-12-02
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.
J.Mol.Biol., 408, 2011
5WNM
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BU of 5wnm by Molmil
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to tozasertib (VX-680)
Descriptor: CHLORIDE ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNL
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BU of 5wnl by Molmil
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to staurosporine
Descriptor: CHLORIDE ION, Receptor-interacting serine/threonine-protein kinase 4, STAUROSPORINE
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNJ
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BU of 5wnj by Molmil
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with lestaurtinib
Descriptor: CHLORIDE ION, Lestaurtinib, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNK
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BU of 5wnk by Molmil
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to TG100-115
Descriptor: 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol, CHLORIDE ION, Receptor-interacting serine/threonine-protein kinase 4
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
5WNI
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BU of 5wni by Molmil
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huang, C.S, Hymowitz, S.G.
Deposit date:2017-08-01
Release date:2018-05-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Structure, 26, 2018
3TMO
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BU of 3tmo by Molmil
The catalytic domain of human deubiquitinase DUBA
Descriptor: OTU domain-containing protein 5
Authors:Yin, J, Bosanac, I, Ma, X, Hymowitz, S, Starovasnik, M, Cochran, A.
Deposit date:2011-08-31
Release date:2012-01-11
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Phosphorylation-dependent activity of the deubiquitinase DUBA.
Nat.Struct.Mol.Biol., 19, 2012

 

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