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5T9D
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BU of 5t9d by Molmil
Structure of PCNA acetylated on K20
Descriptor: Proliferating cell nuclear antigen
Authors:Couture, J.F, Tremblay, V, Brunzelle, J.S.
Deposit date:2016-09-09
Release date:2017-04-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure of PCNA acetylated on K20
To Be Published
1MRQ
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BU of 1mrq by Molmil
Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone
Descriptor: Aldo-keto reductase family 1 member C1, BETA-MERCAPTOETHANOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Couture, J.F, Legrand, P, Cantin, L, Luu-The, V, Labrie, F, Breton, R.
Deposit date:2002-09-18
Release date:2003-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
J.Mol.Biol., 331, 2003
1Q5M
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BU of 1q5m by Molmil
Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin-E2 9-reductase, SULFATE ION
Authors:Couture, J.F, Legrand, P, Cantin, L, Labrie, F, Luu-The, V, Breton, R.
Deposit date:2003-08-08
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Loop Relaxation, A Mechanism that Explains the Reduced Specificity of Rabbit 20alpha-Hydroxysteroid Dehydrogenase, A Member of the Aldo-Keto Reductase Superfamily.
J.Mol.Biol., 339, 2004
2H2J
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BU of 2h2j by Molmil
Structure of Rubisco LSMT bound to Sinefungin and Monomethyllysine
Descriptor: N-METHYL-LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, SINEFUNGIN
Authors:Couture, J.F, Hauk, G, Trievel, R.C.
Deposit date:2006-05-18
Release date:2006-05-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2H14
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BU of 2h14 by Molmil
Crystal of WDR5 (apo-form)
Descriptor: WD-repeat protein 5
Authors:Couture, J.F, Collazo, E, Trievel, R.C.
Deposit date:2006-05-15
Release date:2006-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Molecular recognition of histone H3 by the WD40 protein WDR5.
Nat.Struct.Mol.Biol., 13, 2006
2H2E
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BU of 2h2e by Molmil
Structure of Rubisco LSMT bound to AzaAdoMet and Lysine
Descriptor: LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE
Authors:Couture, J.F, Hauk, G, Trievel, R.C.
Deposit date:2006-05-18
Release date:2006-05-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2H13
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BU of 2h13 by Molmil
Crystal structure of WDR5/histone H3 complex
Descriptor: WD-repeat protein 5, histone H3 lys-4 dimethylated
Authors:Couture, J.F, Collazo, E, Trievel, R.C.
Deposit date:2006-05-15
Release date:2006-07-11
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Molecular recognition of histone H3 by the WD40 protein WDR5.
Nat.Struct.Mol.Biol., 13, 2006
2H21
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BU of 2h21 by Molmil
Structure of Rubisco LSMT bound to AdoMet
Descriptor: Ribulose-1,5 bisphosphate carboxylase/oxygenase, S-ADENOSYLMETHIONINE
Authors:Couture, J.F, Hauk, G, Trievel, R.C.
Deposit date:2006-05-17
Release date:2006-05-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
2H23
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BU of 2h23 by Molmil
Structure of Rubisco LSMT bound to Trimethyllysine and AdoHcy
Descriptor: N-TRIMETHYLLYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Couture, J.F, Hauk, G, Trievel, R.C.
Deposit date:2006-05-17
Release date:2006-05-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases.
J.Biol.Chem., 281, 2006
6O09
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BU of 6o09 by Molmil
Structure of AtPCNA in complex with the PIP motif of ATXR6
Descriptor: Proliferating cellular nuclear antigen 1, Uncharacterized protein
Authors:Couture, J.F, Davarinejad, H.
Deposit date:2019-02-15
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle.
J. Mol. Biol., 431, 2019
6DVS
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BU of 6dvs by Molmil
Crystal structure of Pseudomonas stutzeri D-phenylglycine aminotransferase
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ...
Authors:Couture, J.F, Chica, R.
Deposit date:2018-06-25
Release date:2018-09-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.821 Å)
Cite:Structural Determinants of the Stereoinverting Activity of Pseudomonas stutzeri d-Phenylglycine Aminotransferase.
Biochemistry, 57, 2018
8SKJ
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BU of 8skj by Molmil
Crystal structure of a Nanobody bound to the V5 peptide.
Descriptor: NbA1, V5 Epitope Tag Peptide
Authors:Zaghal, M, Matte, K, Venes, A, Patel, S, Laroche, G, Sarvan, S, Joshi, M, Couture, J.F, Giguere, P.M.
Deposit date:2023-04-19
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signaling.
J.Biol.Chem., 299, 2023
4O30
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BU of 4o30 by Molmil
Crystal structure of ATXR5 in complex with histone H3.1 and AdoHcy
Descriptor: BETA-MERCAPTOETHANOL, DIMETHYL SULFOXIDE, Histone-lysine N-methyltransferase ATXR6, ...
Authors:Bergamin, E, Mongeon, V, Couture, J.F.
Deposit date:2013-12-17
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication.
Science, 343, 2014
6D57
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BU of 6d57 by Molmil
Campylobacter jejuni ferric uptake regulator S1 metalated
Descriptor: FORMIC ACID, Ferric uptake regulation protein, GLYCEROL, ...
Authors:Sarvan, S, Brunzelle, J.S, Couture, J.F.
Deposit date:2018-04-19
Release date:2018-05-23
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Functional insights into the interplay between DNA interaction and metal coordination in ferric uptake regulators.
Sci Rep, 8, 2018
6E2H
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BU of 6e2h by Molmil
Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30
Descriptor: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2
Authors:Joshi, M, Brunzelle, J.S, Couture, J.F.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.236 Å)
Cite:Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation.
Structure, 26, 2018
7TLP
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BU of 7tlp by Molmil
Structure of Atopobium parvulum SufS K235R
Descriptor: Cysteine desulfurase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]
Authors:Karunakaran, G, Couture, J.F.
Deposit date:2022-01-18
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7TLQ
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BU of 7tlq by Molmil
Structure of Atopobium parvulum SufS C375S
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karunakaran, G, Couture, J.F.
Deposit date:2022-01-18
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7TLM
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BU of 7tlm by Molmil
Structure of Atopobium parvulum SufS
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karunakaran, G, Couture, J.F.
Deposit date:2022-01-18
Release date:2022-02-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7TLR
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BU of 7tlr by Molmil
Structure of Atopobium parvulum SufS A34Y mutant
Descriptor: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karunakaran, G, Couture, J.F.
Deposit date:2022-01-18
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7T7T
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BU of 7t7t by Molmil
Structure of TSK/BRU1 bound to histone H3.1
Descriptor: Histone H3.1, Protein TONSOKU
Authors:Davarinejad, H, Couture, J.F.
Deposit date:2021-12-15
Release date:2022-03-30
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Science, 375, 2022
6VHF
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BU of 6vhf by Molmil
Crystal structure of RbBP5 interacting domain of Cfp1
Descriptor: PHD-type domain-containing protein, ZINC ION
Authors:Joshi, M, Couture, J.F.
Deposit date:2020-01-09
Release date:2020-01-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.311 Å)
Cite:A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS.
Nucleic Acids Res., 48, 2020
5VAC
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BU of 5vac by Molmil
Crystal Structure of ATXR5 SET domain in complex with K36me3 histone H3 peptide
Descriptor: DIMETHYL SULFOXIDE, Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, ...
Authors:Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.F.
Deposit date:2017-03-24
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Molecular basis for the methylation specificity of ATXR5 for histone H3.
Nucleic Acids Res., 45, 2017
6DK4
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BU of 6dk4 by Molmil
Crystal structure of Campylobacter jejuni peroxide stress regulator
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Ferric uptake regulation protein, MANGANESE (II) ION, ...
Authors:Sarvan, S, Brunzelle, J.S, Couture, J.F.
Deposit date:2018-05-28
Release date:2018-06-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structure of Campylobacter jejuni peroxide regulator.
FEBS Lett., 592, 2018
6E29
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BU of 6e29 by Molmil
Crystal structure of Myceliophteria_thermophila Cps50 (Swd1) beta-propeller domain
Descriptor: SWD1-like protein
Authors:Joshi, M, Yang, Y, Brunzelle, J.S, Couture, J.F.
Deposit date:2018-07-10
Release date:2018-07-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex.
Cell, 174, 2018
2PNU
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BU of 2pnu by Molmil
Crystal structure of human androgen receptor ligand-binding domain in complex with EM-5744
Descriptor: (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Cantin, L, Faucher, F, Couture, J.F, Pereira de Jesus-Tran, K, Legrand, P, Ciobanu, C.L, Singh, S.M, Labrie, F, Breton, R.
Deposit date:2007-04-25
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Characterization of the Human Androgen Receptor Ligand-binding Domain Complexed with EM5744, a Rationally Designed Steroidal Ligand Bearing a Bulky Chain Directed toward Helix 12.
J.Biol.Chem., 282, 2007

 

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