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1BT7
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BU of 1bt7 by Molmil
THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES
Descriptor: NS3 SERINE PROTEASE, ZINC ION
Authors:Barbato, G, Cicero, D.O, Nardi, M.C, Steinkuhler, C, Cortese, R, De Francesco, R, Bazzo, R.
Deposit date:1998-09-01
Release date:1999-06-22
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism.
J.Mol.Biol., 289, 1999
1MZI
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BU of 1mzi by Molmil
Solution ensemble structures of HIV-1 gp41 2F5 mAb epitope
Descriptor: 2F5 epitope of HIV-1 gp41 fusion protein
Authors:Barbato, G, Bianchi, E, Ingallinella, P, Hurni, W.H, Miller, M.D, Ciliberto, G, Cortese, R, Bazzo, R, Shiver, J.W, Pessi, A.
Deposit date:2002-10-08
Release date:2003-09-02
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion.
J.Mol.Biol., 330, 2003
2VGO
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BU of 2vgo by Molmil
Crystal structure of Aurora B kinase in complex with Reversine inhibitor
Descriptor: INNER CENTROMERE PROTEIN A, N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine, SERINE/THREONINE-PROTEIN KINASE 12-A
Authors:D'Alise, A.M, Amabile, G, Iovino, M, Di Giorgio, F.P, Bartiromo, M, Sessa, F, Villa, F, Musacchio, A, Cortese, R.
Deposit date:2007-11-15
Release date:2008-10-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Reversine, a Novel Aurora Kinases Inhibitor, Inhibits Colony Formation of Human Acute Myeloid Leukemia Cells.
Mol.Cancer Ther., 7, 2008
1H0M
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BU of 1h0m by Molmil
Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA
Descriptor: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP *CP*TP*GP*CP*AP*CP*AP*T)-3', Transcriptional activator protein TraR
Authors:Vannini, A, Volpari, C, Gargioli, C, Muraglia, E, Cortese, R, De Francesco, R, Neddermann, P, Di Marco, S.
Deposit date:2002-06-25
Release date:2002-08-29
Last modified:2020-12-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of the Quorum Sensing Protein Trar Bound to its Autoinducer and Target DNA
Embo J., 21, 2002
1LFB
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BU of 1lfb by Molmil
THE X-RAY STRUCTURE OF AN ATYPICAL HOMEODOMAIN PRESENT IN THE RAT LIVER TRANSCRIPTION FACTOR LFB1(SLASH)HNF1 AND IMPLICATIONS FOR DNA BINDING
Descriptor: LIVER TRANSCRIPTION FACTOR (LFB1)
Authors:Ceska, T.A, Lamers, M, Monaci, P, Nicosia, A, Cortese, R, Suck, D.
Deposit date:1993-06-28
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding.
EMBO J., 12, 1993
1DXW
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BU of 1dxw by Molmil
structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound
Descriptor: N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, SERINE PROTEASE, ZINC ION
Authors:Barbato, G, Cicero, D.O, Cordier, F, Narjes, F, Gerlach, B, Sambucini, S, Grzesiek, S, Matassa, V.G, Defrancesco, R, Bazzo, R.
Deposit date:2000-01-17
Release date:2001-01-12
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Inhibitor Binding Induces Active Site Stabilisation of the Hcv Ns3 Protein Serine Protease Domain
Embo J., 19, 2000
1OL0
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Crystal structure of a camelised human VH
Descriptor: GLYCEROL, IMMUNOGLOBULIN G, SULFATE ION
Authors:Dottorini, T, Vaughan, C.K, Walsh, M.A, Losurdo, P, Sollazzo, M.
Deposit date:2003-08-02
Release date:2004-01-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Human Vh: Requirements for Maintaining a Monomeric Fragment
Biochemistry, 43, 2004
2LFB
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HOMEODOMAIN FROM RAT LIVER LFB1/HNF1 TRANSCRIPTION FACTOR, NMR, 20 STRUCTURES
Descriptor: LFB1/HNF1 TRANSCRIPTION FACTOR
Authors:Schott, O, Billeter, M, Leiting, B, Wider, G, Wuthrich, K.
Deposit date:1996-12-12
Release date:1997-03-12
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The NMR solution structure of the non-classical homeodomain from the rat liver LFB1/HNF1 transcription factor.
J.Mol.Biol., 267, 1997

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