2A4N
 
 | | Crystal structure of aminoglycoside 6'-N-acetyltransferase complexed with coenzyme A | | Descriptor: | COENZYME A, SULFATE ION, aac(6')-Ii | | Authors: | Burk, D.L, Xiong, B, Breitbach, C, Berghuis, A.M. | | Deposit date: | 2005-06-29 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of aminoglycoside acetyltransferase AAC(6')-Ii in a novel crystal form: structural and normal-mode analyses.
Acta Crystallogr.,Sect.D, 61, 2005
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1N71
 | | Crystal structure of aminoglycoside 6'-acetyltransferase type Ii in complex with coenzyme A | | Descriptor: | COENZYME A, SULFATE ION, aac(6')-Ii | | Authors: | Burk, D.L, Ghuman, N, Wybenga-Groot, L.E, Berghuis, A.M. | | Deposit date: | 2002-11-12 | | Release date: | 2003-03-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members
Protein Sci., 12, 2003
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1J7U
 | | Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa AMPPNP Complex | | Descriptor: | AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M. | | Deposit date: | 2001-05-18 | | Release date: | 2001-08-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001
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1J7L
 | | Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, MAGNESIUM ION | | Authors: | Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M. | | Deposit date: | 2001-05-17 | | Release date: | 2001-08-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001
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1J7I
 | | Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Apoenzyme | | Descriptor: | AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE | | Authors: | Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M. | | Deposit date: | 2001-05-16 | | Release date: | 2001-08-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001
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2Q99
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1RSE
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1HRM
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5E96
 | | Crystal structure of aminoglycoside 6'-acetyltransferase type Ii | | Descriptor: | 1,2-ETHANEDIOL, Aminoglycoside 6'-acetyltransferase, PHOSPHATE ION | | Authors: | Berghuis, A.M, Burk, D.L, Baettig, O.M, Shi, K. | | Deposit date: | 2015-10-14 | | Release date: | 2016-07-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Comprehensive characterization of ligand-induced plasticity changes in a dimeric enzyme.
Febs J., 283, 2016
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4I59
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4I58
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5IGH
 | | Macrolide 2'-phosphotransferase type I | | Descriptor: | Macrolide 2'-phosphotransferase, SULFATE ION | | Authors: | Berghuis, A.M, Fong, D.H. | | Deposit date: | 2016-02-28 | | Release date: | 2017-04-26 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
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5IGV
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5IGR
 | | Macrolide 2'-phosphotransferase type I - complex with GDP and oleandomycin | | Descriptor: | (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, AMMONIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Berghuis, A.M, Fong, D.H. | | Deposit date: | 2016-02-28 | | Release date: | 2017-04-26 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
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5IH1
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5IGU
 | | Macrolide 2'-phosphotransferase type II | | Descriptor: | Macrolide 2'-phosphotransferase II | | Authors: | Berghuis, A.M, Fong, D.H. | | Deposit date: | 2016-02-28 | | Release date: | 2017-04-26 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
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5IH0
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5IGJ
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5IGW
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5IGP
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5IGZ
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5IGI
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5IGT
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5IGY
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5IGS
 | | Macrolide 2'-phosphotransferase type I - complex with guanosine and oleandomycin | | Descriptor: | (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, GUANOSINE, ISOPROPYL ALCOHOL, ... | | Authors: | Berghuis, A.M, Fong, D.H. | | Deposit date: | 2016-02-28 | | Release date: | 2017-04-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
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