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1SPJ
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BU of 1spj by Molmil
STRUCTURE OF MATURE HUMAN TISSUE KALLIKREIN (HUMAN KALLIKREIN 1 OR KLK1) AT 1.70 ANGSTROM RESOLUTION WITH VACANT ACTIVE SITE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ...
Authors:Laxmikanthan, G, Blaber, S.I, Bernett, M.J, Blaber, M.
Deposit date:2004-03-16
Release date:2005-01-25
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:1.70 A X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding
Proteins, 58, 2005
1JT5
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Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)
Descriptor: SULFATE ION, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT4
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BU of 1jt4 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L)
Descriptor: FORMIC ACID, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT7
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BU of 1jt7 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)
Descriptor: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JTC
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BU of 1jtc by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F)
Descriptor: FORMIC ACID, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JQZ
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BU of 1jqz by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag.
Descriptor: FORMIC ACID, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
Deposit date:2001-08-09
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT3
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BU of 1jt3 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V)
Descriptor: SULFATE ION, acidic fibroblast growth factor
Authors:Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
Deposit date:2001-08-20
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1K5U
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BU of 1k5u by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with His93 replaced by Gly (H93G).
Descriptor: Acidic fibroblast growth factor, SULFATE ION
Authors:Kim, J, Blaber, S.I, Blaber, M.
Deposit date:2001-10-12
Release date:2002-02-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
1K5V
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BU of 1k5v by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with Asn106 replaced by Gly (N106G).
Descriptor: Acidic fibroblast growth factor, SULFATE ION
Authors:Kim, J, Blaber, S.I, Blaber, M.
Deposit date:2001-10-12
Release date:2002-02-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
1LO6
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BU of 1lo6 by Molmil
Human Kallikrein 6 (hK6) active form with benzamidine inhibitor at 1.56 A resolution
Descriptor: BENZAMIDINE, Kallikrein 6, MAGNESIUM ION
Authors:Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Dhanarajan, P, Thompson, S.M, Blaber, M.
Deposit date:2002-05-06
Release date:2002-05-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure and biochemical characterization of human kallikrein 6 reveals a trypsin-like kallikrein is expressed in the central nervous system
To be Published
1L2E
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BU of 1l2e by Molmil
Human Kallikrein 6 (hK6) Active Form with benzamidine inhibitor
Descriptor: BENZAMIDINE, Kallikrein 6, MAGNESIUM ION
Authors:Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Blaber, M.
Deposit date:2002-02-20
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system.
J.Biol.Chem., 277, 2002
4YOL
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BU of 4yol by Molmil
Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
Descriptor: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
Authors:Xia, X, Blaber, M.
Deposit date:2015-03-11
Release date:2016-03-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.
J.Pharm.Sci., 105, 2016
3HAL
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BU of 3hal by Molmil
Crystal structure of Rabbit acidic fibroblast growth factor
Descriptor: CHLORIDE ION, Fibroblast growth factor 1 isoform 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2009-05-01
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure and biophysical properties of rabbit fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3O3Q
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BU of 3o3q by Molmil
Crystal structure of "L44F/M67I/L73V/A103G/deletion 104-106/F108Y/V109L/L111I/C117V/R119G/deletion 120-122" mutant form of Human acidic fibroblast growth factor
Descriptor: GLYCEROL, Heparin-binding growth factor 1
Authors:Lee, J, Blaber, M.
Deposit date:2010-07-25
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A polypeptide "building block"top-down symmetric deconstruction".
J.Mol.Biol., 407, 2011
3CRG
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BU of 3crg by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala
Descriptor: FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ...
Authors:Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2008-04-07
Release date:2009-02-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CQA
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BU of 3cqa by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2008-04-02
Release date:2009-04-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CRI
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BU of 3cri by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2008-04-07
Release date:2009-02-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CRH
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BU of 3crh by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
Deposit date:2008-04-07
Release date:2009-02-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009

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