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8DUZ
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BU of 8duz by Molmil
Protective antibody against gonococcal lipooligosaccharide bound to peptide mimetic
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Beernink, P.T, Beernink, B.P, Rice, P.A, Ram, S.
Deposit date:2022-07-27
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Protective antibody against gonococcal lipooligosaccharide bound to peptide mimetic
to be published
8DOZ
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BU of 8doz by Molmil
Protective antibody against gonococcal lipooligosaccharide
Descriptor: ACETATE ION, Fab 2C7 lambda light chain, Fab 2C7, ...
Authors:Beernink, P.T.
Deposit date:2022-07-14
Release date:2023-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protective antibody against gonococcal lipooligosaccharide bound to a peptide mimetic vaccine antigen
TBD
3CSU
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BU of 3csu by Molmil
CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE
Descriptor: CALCIUM ION, PROTEIN (ASPARTATE CARBAMOYLTRANSFERASE)
Authors:Beernink, P.T, Endrizzi, J.A, Alber, T, Schachman, H.K.
Deposit date:1999-04-22
Release date:1999-05-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Assessment of the allosteric mechanism of aspartate transcarbamoylase based on the crystalline structure of the unregulated catalytic subunit.
Proc.Natl.Acad.Sci.USA, 96, 1999
1E9N
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BU of 1e9n by Molmil
A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism
Descriptor: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
Authors:Beernink, P.T, Segelke, B.W, Rupp, B.
Deposit date:2000-10-24
Release date:2001-02-16
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1HD7
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BU of 1hd7 by Molmil
A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism
Descriptor: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
Authors:Beernink, P.T, Segelke, B.W, Rupp, B.
Deposit date:2000-11-09
Release date:2001-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
7KE1
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BU of 7ke1 by Molmil
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: CHLORIDE ION, Immunoglobulin gamma, heavy chain Fd fragment, ...
Authors:Beernink, P.T, Sands, N.
Deposit date:2020-10-09
Release date:2021-06-09
Last modified:2021-07-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
Plos Pathog., 17, 2021
7KET
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BU of 7ket by Molmil
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: Factor H binding protein, Immunoglobulin gamma, heavy chain Fd fragment, ...
Authors:Beernink, P.T, Sands, N.
Deposit date:2020-10-12
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
Plos Pathog., 17, 2021
7LCV
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BU of 7lcv by Molmil
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: CHLORIDE ION, Factor H binding protein, Immunoglobulin heavy chain Fd fragment, ...
Authors:Beernink, P.T, Sands, N.
Deposit date:2021-01-11
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
Plos Pathog., 17, 2021
5UR8
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BU of 5ur8 by Molmil
Human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: human immunoglobulin gamma, heavy chain Fd fragment, kappa light chain
Authors:Beernink, P.T.
Deposit date:2017-02-09
Release date:2018-02-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75500226 Å)
Cite:Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Nat Commun, 9, 2018
5VMQ
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BU of 5vmq by Molmil
STRUCTURE OF THE R105A MUTANT CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE AT 2.0-A RESOLUTION
Descriptor: Aspartate carbamoyltransferase, CALCIUM ION, CHLORIDE ION
Authors:Beernink, P.T, Endrizzi, J.A.
Deposit date:2017-04-28
Release date:2017-05-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.012 Å)
Cite:Charge neutralization in the active site of the catalytic trimer of aspartate transcarbamoylase promotes diverse structural changes.
Protein Sci., 26, 2017
4Z3T
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BU of 4z3t by Molmil
Meningococcal Factor H binding protein mutant L130R/G133D
Descriptor: Factor H binding protein variant A10_001, MAGNESIUM ION
Authors:Konar, M, Beernink, P.T.
Deposit date:2015-03-31
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:A meningococcal vaccine antigen engineered to increase thermal stability and stabilize protective epitopes.
Proc.Natl.Acad.Sci.USA, 112, 2015
1HJ6
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BU of 1hj6 by Molmil
ISOCITRATE DEHYDROGENASE S113E MUTANT COMPLEXED WITH ISOPROPYLMALATE, NADP+ AND MAGNESIUM (FLASH-COOLED)
Descriptor: 3-ISOPROPYLMALIC ACID, GLYCEROL, ISOCITRATE DEHYDROGENASE, ...
Authors:Doyle, S.A, Beernink, P.T, Koshland Junior, D.E.
Deposit date:2001-01-08
Release date:2001-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for a Change in Substrate Specificity: Crystal Structure of S113E Isocitrate Dehydrogenase in a Complex with Isopropylmalate, Mg2+ and Nadp
Biochemistry, 40, 2001
1EKX
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BU of 1ekx by Molmil
THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE)
Descriptor: ASPARTATE TRANSCARBAMOYLASE, CALCIUM ION, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
Authors:Endrizzi, J.A, Beernink, P.T, Alber, T, Schachman, H.K.
Deposit date:2000-03-09
Release date:2000-05-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration.
Proc.Natl.Acad.Sci.USA, 97, 2000
5O14
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BU of 5o14 by Molmil
Co-crystal structure of a cross-reactive bactericidal human antibody targeting meningococcal vaccine antigen factor H binding protein
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Fab 1A12 Heavy Chain, ...
Authors:Lopez-Sagaseta, J.
Deposit date:2017-05-18
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Nat Commun, 9, 2018
5T5F
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BU of 5t5f by Molmil
Neisseria meningitidis factor H binding protein in complex with monoclonal antibody JAR5
Descriptor: Factor H binding protein variant B24, Monoclonal antibody Jar5 heavy chain, Monoclonal antibody Jar5 light chain
Authors:Malito, E.
Deposit date:2016-08-30
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy.
Biochem. J., 473, 2016

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PDB entries from 2024-03-27

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