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1LF5
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BU of 1lf5 by Molmil
Crystal Structure of RasA59G in the GDP-bound Form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein P21/H-RAS-1
Authors:Hall, B.E, Bar-Sagi, D, Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
1LF0
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BU of 1lf0 by Molmil
Crystal Structure of RasA59G in the GTP-bound form
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Hall, B.E, Bar-Sagi, D, Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
2II0
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BU of 2ii0 by Molmil
Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras
Descriptor: Son of sevenless homolog 1
Authors:Freedman, T.S, Sondermann, H, Friedland, G.D, Kortemme, T, Bar-Sagi, D, Marqusee, S, Kuriyan, J.
Deposit date:2006-09-27
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A Ras-induced conformational switch in the Ras activator Son of sevenless.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1XDV
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BU of 1xdv by Molmil
Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Descriptor: Son of sevenless protein homolog 1
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-08
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1XD4
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BU of 1xd4 by Molmil
Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
Descriptor: Son of sevenless protein homolog 1
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-03
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1XD2
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BU of 1xd2 by Molmil
Crystal Structure of a ternary Ras:SOS:Ras*GDP complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-03
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1NVV
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BU of 1nvv by Molmil
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1NVW
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BU of 1nvw by Molmil
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1NVX
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BU of 1nvx by Molmil
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1NVU
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BU of 1nvu by Molmil
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1Q9C
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BU of 1q9c by Molmil
Crystal Structure of the Histone domain of Son of Sevenless
Descriptor: Son of sevenless protein
Authors:Sondermann, H, Soisson, S.M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-08-24
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Tandem Histone Folds in the Structure of the N-terminal Segment of the Ras Activator Son of Sevenless
Structure, 11, 2003
1AWE
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BU of 1awe by Molmil
HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES
Descriptor: SOS1
Authors:Zheng, J, Cowburn, D.
Deposit date:1997-10-01
Release date:1998-02-25
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
J.Biol.Chem., 272, 1997
1BKD
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BU of 1bkd by Molmil
COMPLEX OF HUMAN H-RAS WITH HUMAN SOS-1
Descriptor: H-RAS, SON OF SEVENLESS-1
Authors:Boriack-Sjodin, P.A, Margarit, S.M, Sagi, D.B, Kuriyan, J.
Deposit date:1998-07-06
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of the activation of Ras by Sos.
Nature, 394, 1998
1DBH
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BU of 1dbh by Molmil
DBL AND PLECKSTRIN HOMOLOGY DOMAINS FROM HSOS1
Descriptor: PROTEIN (HUMAN SOS 1)
Authors:Soisson, S.M, Kuriyan, J.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.
Cell(Cambridge,Mass.), 95, 1998
3KSY
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BU of 3ksy by Molmil
Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)
Descriptor: Son of sevenless homolog 1
Authors:Gureasko, J, Kuchment, O, Kuriyan, J.
Deposit date:2009-11-24
Release date:2010-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.178 Å)
Cite:Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
Proc.Natl.Acad.Sci.USA, 107, 2010
2IJE
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BU of 2ije by Molmil
Crystal Structure of the Cdc25 domain of RasGRF1
Descriptor: GLYCEROL, Guanine nucleotide-releasing protein
Authors:Freedman, T.S, Kuriyan, J.
Deposit date:2006-09-29
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Ras-induced conformational switch in the Ras activator Son of sevenless.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZW6
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BU of 1zw6 by Molmil
Crystal Structure of the GTP-bound form of RasQ61G
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Ford, B, Hornak, V, Kleinman, H, Nassar, N.
Deposit date:2005-06-03
Release date:2006-03-14
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006
1ZVQ
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BU of 1zvq by Molmil
Structure of the Q61G mutant of Ras in the GDP-bound form
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein p21/H-Ras-1
Authors:Ford, B, Nassar, N.
Deposit date:2005-06-02
Release date:2006-03-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006

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