Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1ASW
DownloadVisualize
BU of 1asw by Molmil
AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 20% PEG 4000, 10% ISOPROPANOL, HEPES PH 7.5 USING SELENOMETHIONINE SUBSTITUTED PROTEIN; DATA COLLECTED AT-165 DEGREES C
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE, ISOPROPYL ALCOHOL
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-08-25
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J.Mol.Biol., 253, 1995
1ASU
DownloadVisualize
BU of 1asu by Molmil
AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 2% PEG 400, 2M AMMONIUM SULFATE, HEPES PH 7.5
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-08-25
Release date:1995-11-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J.Mol.Biol., 253, 1995
2ITG
DownloadVisualize
BU of 2itg by Molmil
CATALYTIC DOMAIN OF HIV-1 INTEGRASE: ORDERED ACTIVE SITE IN THE F185H CONSTRUCT
Descriptor: HUMAN IMMUNODEFICIENCY VIRUS-1 INTEGRASE
Authors:Bujacz, G, Alexandratos, J, Wlodawer, A, Zhou-Liu, Q, Clement-Mella, C.
Deposit date:1996-09-13
Release date:1997-03-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant.
FEBS Lett., 398, 1996
1A5V
DownloadVisualize
BU of 1a5v by Molmil
ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3 AND MN CATION
Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE, MANGANESE (II) ION
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
1A5W
DownloadVisualize
BU of 1a5w by Molmil
ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3
Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
1A5X
DownloadVisualize
BU of 1a5x by Molmil
ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3
Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
1ASV
DownloadVisualize
BU of 1asv by Molmil
Avian sarcoma virus integrase catalytic core domain
Descriptor: AVIAN SARCOMA VIRUS INTEGRASE
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-08-25
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J.Mol.Biol., 253, 1995
1CXU
DownloadVisualize
BU of 1cxu by Molmil
1.42A RESOLUTION ASV INTEGRASE CORE DOMAIN FROM CITRATE
Descriptor: CITRIC ACID, GLYCEROL, PROTEIN (AVIAN SARCOMA VIRUS INTEGRASE)
Authors:Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1999-08-30
Release date:1999-09-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
2B7F
DownloadVisualize
BU of 2b7f by Molmil
Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design
Descriptor: (ACE)APQV(STA)VMHP peptide, HTLV protease, PHOSPHATE ION
Authors:Li, M, Laco, G.S, Jaskolski, M, Rozycki, J, Alexandratos, J, Wlodawer, A, Gustchina, A.
Deposit date:2005-10-04
Release date:2005-12-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design
Proc.Natl.Acad.Sci.Usa, 102, 2005
1CXQ
DownloadVisualize
BU of 1cxq by Molmil
ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM AMMONIUM SULFATE
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE, GLYCEROL
Authors:Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Merkel, G, Skalka, A.M, Wlodawer, A.
Deposit date:1999-08-30
Release date:1999-09-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
1CZB
DownloadVisualize
BU of 1czb by Molmil
ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM HEPES
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE
Authors:Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Merkel, G, Skalka, A.M, Wlodawer, A.
Deposit date:1999-09-01
Release date:1999-09-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
1CZ9
DownloadVisualize
BU of 1cz9 by Molmil
ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN (D64N) FROM CITRATE
Descriptor: AVIAN SARCOMA VIRUS INTEGRASE, CITRIC ACID, SULFATE ION
Authors:Lubkowski, J, Dauter, Z, Yang, F, Alexandratos, J, Merkel, G, Skalka, A.M, Wlodawer, A.
Deposit date:1999-09-01
Release date:1999-09-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Atomic resolution structures of the core domain of avian sarcoma virus integrase and its D64N mutant.
Biochemistry, 38, 1999
1ZPA
DownloadVisualize
BU of 1zpa by Molmil
HIV Protease with Scripps AB-3 Inhibitor
Descriptor: Pol polyprotein, TERT-BUTYL 4-[({[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}AMINO)CARBONYL]BENZYLCARBAMATE
Authors:Brik, A, Alexandratos, J, Lin, Y.C, Elder, J.H, Olson, A.J, Wlodawer, A, Goodsell, D.S, Wong, C.H.
Deposit date:2005-05-16
Release date:2005-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors
Chembiochem, 6, 2005
1VSL
DownloadVisualize
BU of 1vsl by Molmil
ASV INTEGRASE CORE DOMAIN D64N MUTATION WITH ZINC CATION
Descriptor: PROTEIN (INTEGRASE), ZINC ION
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-09-18
Release date:1998-09-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for inactivating mutations and pH-dependent activity of avian sarcoma virus integrase.
J.Biol.Chem., 273, 1998
1VSM
DownloadVisualize
BU of 1vsm by Molmil
ASV INTEGRASE CORE DOMAIN IN CITRATE BUFFER PH 5.0
Descriptor: PROTEIN (INTEGRASE)
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-09-18
Release date:1998-09-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for inactivating mutations and pH-dependent activity of avian sarcoma virus integrase.
J.Biol.Chem., 273, 1998
1VSK
DownloadVisualize
BU of 1vsk by Molmil
ASV INTEGRASE CORE DOMAIN D64N MUTATION IN CITRATE BUFFER PH 6.0
Descriptor: INTEGRASE
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-09-18
Release date:1998-12-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for inactivating mutations and pH-dependent activity of avian sarcoma virus integrase.
J.Biol.Chem., 273, 1998
1VSD
DownloadVisualize
BU of 1vsd by Molmil
ASV INTEGRASE CORE DOMAIN WITH MG(II) COFACTOR AND HEPES LIGAND, HIGH MG CONCENTRATION FORM
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, MAGNESIUM ION
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.
Structure, 4, 1996
1VSH
DownloadVisualize
BU of 1vsh by Molmil
ASV INTEGRASE CORE DOMAIN WITH ZN(II) COFACTORS
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, ZINC ION
Authors:Bujacz, G, Alexandratos, J, Wlodawer, A.
Deposit date:1997-03-04
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity.
J.Biol.Chem., 272, 1997
1VSF
DownloadVisualize
BU of 1vsf by Molmil
ASV INTEGRASE CORE DOMAIN WITH MN(II) COFACTOR AND HEPES LIGAND, HIGH MG CONCENTRATION FORM
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, MANGANESE (II) ION
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.
Structure, 4, 1996
1VSE
DownloadVisualize
BU of 1vse by Molmil
ASV INTEGRASE CORE DOMAIN WITH MG(II) COFACTOR AND HEPES LIGAND, LOW MG CONCENTRATION FORM
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE
Authors:Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations.
Structure, 4, 1996
1VSJ
DownloadVisualize
BU of 1vsj by Molmil
ASV INTEGRASE CORE DOMAIN WITH CD(II) COFACTORS
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, INTEGRASE
Authors:Bujacz, G, Alexandratos, J, Wlodawer, A.
Deposit date:1997-03-04
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity.
J.Biol.Chem., 272, 1997
1VSI
DownloadVisualize
BU of 1vsi by Molmil
ASV INTEGRASE CORE DOMAIN WITH CA(II) COFACTOR
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, INTEGRASE
Authors:Bujacz, G, Alexandratos, J, Wlodawer, A.
Deposit date:1997-03-04
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity.
J.Biol.Chem., 272, 1997
7R6A
DownloadVisualize
BU of 7r6a by Molmil
Crystal structure of mutant L124D/R125A/C273S of L-Asparaginase I from Yersinia pestis
Descriptor: FORMIC ACID, L-asparaginase I
Authors:Strzelczyk, P, Wlodawer, A, Lubkowski, J.
Deposit date:2021-06-22
Release date:2022-07-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The dimeric form of bacterial l-asparaginase YpAI is fully active.
Febs J., 290, 2023
7R6B
DownloadVisualize
BU of 7r6b by Molmil
Crystal structure of mutant R43D/L124D/R125A/C273S of L-Asparaginase I from Yersinia pestis
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, L-asparaginase I
Authors:Strzelczyk, P, Wlodawer, A, Lubkowski, J.
Deposit date:2021-06-22
Release date:2022-07-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The dimeric form of bacterial l-asparaginase YpAI is fully active.
Febs J., 290, 2023
7R69
DownloadVisualize
BU of 7r69 by Molmil
Crystal structure of mutant R43D/C273S of L-Asparaginase I from Yersinia pestis
Descriptor: 1,2-ETHANEDIOL, L-asparaginase I
Authors:Strzelczyk, P, Wlodawer, A, Lubkowski, J.
Deposit date:2021-06-22
Release date:2022-07-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The dimeric form of bacterial l-asparaginase YpAI is fully active.
Febs J., 290, 2023

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon