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1ASH
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THE STRUCTURE OF ASCARIS HEMOGLOBIN DOMAIN I AT 2.2 ANGSTROMS RESOLUTION: MOLECULAR FEATURES OF OXYGEN AVIDITY
Descriptor:HEMOGLOBIN (DOMAIN ONE)
Authors:Yang, J., Mathews, F.S., Kloek, A.P., Goldberg, D.E.
Deposit date:1995-01-06
Release date:1995-02-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity.
Proc.Natl.Acad.Sci.USA, 92, 1995
2MWN
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TALIN-F3 / RIAM N-TERMINAL PEPTIDE COMPLEX
Descriptor:Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1
Authors:Yang, J., Zhu, L., Zhang, H., Hirbawi, J., Fukuda, K., Dwivedi, P., Liu, J., Byzova, T., Plow, E.F., Wu, J., Qin, J.
Deposit date:2014-11-13
Release date:2014-12-17
Modification date:2015-01-14
Method:SOLUTION NMR
Cite:Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
Nat Commun, 5, 2014
3PYY
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DISCOVERY AND CHARACTERIZATION OF A CELL-PERMEABLE, SMALL-MOLECULE C-ABL KINASE ACTIVATOR THAT BINDS TO THE MYRISTOYL BINDING SITE
Descriptor:V-abl Abelson murine leukemia viral oncogene homolog 1 isoform b variant
Authors:Yang, J., Campobasso, N., Biju, M.P., Fisher, K., Pan, X.Q., Cottom, J., Galbraith, S., Ho, T., Zhang, H., Hong, X, Ward, P., Hofmann, G., Siegfried, B.
Deposit date:2010-12-13
Release date:2011-03-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site.
Chem.Biol., 18, 2011
3QAL
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CRYSTAL STRUCTURE OF ARG280ALA MUTANT OF CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha (E.C.2.7.11.11), Protein kinase inhibitor
Authors:Yang, J., Wu, J., Steichen, J., Taylor, S.S.
Deposit date:2011-01-11
Release date:2011-12-07
Modification date:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
3QAM
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CRYSTAL STRUCTURE OF GLU208ALA MUTANT OF CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha (E.C.2.7.11.11), Protein kinase inhibitor
Authors:Yang, J., Wu, J., Steichen, J., Taylor, S.S.
Deposit date:2011-01-11
Release date:2011-12-07
Modification date:2013-06-19
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
1H6G
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ALPHA-CATENIN M-DOMAIN
Descriptor:ALPHA-1 CATENIN
Authors:Yang, J., Dokurno, P., Tonks, N.K., Barford, D.
Deposit date:2001-06-14
Release date:2001-08-07
Modification date:2016-02-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the M-Fragment of Alpha-Catenin: Implications for Modulation of Cell Adhesion.
Embo J., 20, 2001
1RDQ
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HYDROLYSIS OF ATP IN THE CRYSTAL OF Y204A MUTANT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase, alpha-catalytic subunit (E.C.2.7.1.37)/cAMP-dependent protein kinase inhibitor, alpha form
Authors:Yang, J., Ten Eyck, L.F., Xuong, N.H., Taylor, S.S.
Deposit date:2003-11-05
Release date:2004-04-13
Modification date:2014-01-22
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism.
J.Mol.Biol., 336, 2004
2KNC
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PLATELET INTEGRIN ALFAIIB-BETA3 TRANSMEMBRANE-CYTOPLASMIC HETEROCOMPLEX
Descriptor:Integrin alpha-IIb, Integrin beta-3
Authors:Yang, J., Ma, Y., Page, R.C., Misra, S., Plow, E.F., Qin, J.
Deposit date:2009-08-20
Release date:2009-09-29
Modification date:2011-08-10
Method:SOLUTION NMR
Cite:Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
4NNG
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Modification date:2015-09-09
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4NNH
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Modification date:2015-09-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4NNI
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Modification date:2015-09-09
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
4NNK
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STRUCTURAL BASIS FOR TARGETING THE RIBOSOMAL PROTEIN S1 OF MYCOBACTERIUM TUBERCULOSIS BY PYRAZINAMIDE
Descriptor:30S ribosomal protein S1
Authors:Yang, J., Liu, Y., Cai, Q., Lin, D.
Deposit date:2013-11-18
Release date:2014-12-24
Modification date:2015-09-09
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
1F9P
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CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID
Descriptor:CONNECTIVE TISSUE ACTIVATING PEPTIDE-III
Authors:Yang, J., Faulk, T., Aster, R., Visentin, G., Edwards, B., Castor, C.
Deposit date:2000-07-11
Release date:2003-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure of the CXC Chemokine, Connective Tissue Activating Peptide-III, Complexed with the Heparin Analogue, Polyvinylsulfonic Acid
To be Published
1F9Q
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4
Descriptor:PLATELET FACTOR 4
Authors:Yang, J., Doyle, M., Faulk, T., Visentin, G., Aster, R., Edwards, B.
Deposit date:2000-07-11
Release date:2003-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-Type Reveals the Epitopes for the Heparin-Induced Thrombocytopenia Antibodies
To be Published
1F9R
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1
Descriptor:PLATELET FACTOR 4
Authors:Yang, J., Doyle, M., Faulk, T., Visentin, G., Aster, R., Edwards, B.
Deposit date:2000-07-11
Release date:2003-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies
To be Published
1F9S
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CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 2
Descriptor:PLATELET FACTOR 4
Authors:Yang, J., Doyle, M., Faulk, T., Visentin, G., Aster, R., Edwards, B.
Deposit date:2000-07-11
Release date:2003-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure Comparison of Two Platelet Factor 4 Mutants with the Wild-type Reveals the Epitopes for the Heparin-induced Thrombocytopenia Antibodies
To be Published
1FPR
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1.
Descriptor:PROTEIN-TYROSINE PHOSPHATASE 1C (E.C.3.1.3.48)
Authors:Yang, J., Cheng, Z., Niu, Z., Zhao, Z.J., Zhou, G.W.
Deposit date:2000-08-31
Release date:2001-03-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 275, 2000
1GWZ
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1
Descriptor:SHP-1
Authors:Yang, J., Liang, X., Niu, T., Meng, W., Zhao, Z., Zhou, G.W.
Deposit date:1998-08-22
Release date:1999-08-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 273, 1998
1O6K
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STRUCTURE OF ACTIVATED FORM OF PKB KINASE DOMAIN S474D WITH GSK3 PEPTIDE AND AMP-PNP
Descriptor:RAC-BETA SERINE/THREONINE PROTEIN KINASE (E.C.2.7.1.-), GLYCOGEN SYNTHASE KINASE-3 BETA (E.C.2.7.1.37)
Authors:Yang, J., Cron, P., Good, V.M., Thompson, V., Hemmings, B.A., Barford, D.
Deposit date:2002-10-08
Release date:2002-11-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
1O6L
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CRYSTAL STRUCTURE OF AN ACTIVATED AKT/PROTEIN KINASE B (PKB-PIF CHIMERA) TERNARY COMPLEX WITH AMP-PNP AND GSK3 PEPTIDE
Descriptor:RAC-BETA SERINE/THREONINE PROTEIN KINASE (E.C.2.7.1.-), GLYCOGEN SYNTHASE KINASE-3 BETA (E.C.2.7.1.37)
Authors:Yang, J., Cron, P., Good, V.M., Thompson, V., Hemmings, B.A., Barford, D.
Deposit date:2002-10-08
Release date:2002-11-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
1RE5
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CRYSTAL STRUCTURE OF 3-CARBOXY-CIS,CIS-MUCONATE LACTONIZING ENZYME FROM PSEUDOMONAS PUTIDA
Descriptor:3-carboxy-cis,cis-muconate cycloisomerase
Authors:Yang, J., Wang, Y., Woolridge, E.M., Petsko, G.A., Kozarich, J.W., Ringe, D.
Deposit date:2003-11-06
Release date:2004-06-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of 3-Carboxy-cis,cis-muconate Lactonizing Enzyme from Pseudomonas putida, a Fumarase Class II Type Cycloisomerase: Enzyme Evolution in Parallel Pathways.
Biochemistry, 43, 2004
1RXT
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CRYSTAL STRUCTURE OF HUMAN MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE.
Descriptor:Glycylpeptide N-tetradecanoyltransferase (E.C.2.3.1.97)
Authors:Yang, J., Wang, Y., Frey, G., Abeles, R.H., Petsko, G.A., Ringe, D.
Deposit date:2003-12-18
Release date:2005-04-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase
To be Published
2ASI
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ASPARTIC PROTEINASE
Descriptor:ASPARTIC PROTEINASE
Authors:Yang, J., Jia, Z., Vandonselaar, M., Kepliakov, P.S.A., Quail, J.W.
Deposit date:1995-12-09
Release date:1996-08-01
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution.
J.Mol.Biol., 268, 1997
2B3O
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CRYSTAL STRUCTURE OF HUMAN TYROSINE PHOSPHATASE SHP-1
Descriptor:Tyrosine-protein phosphatase, non-receptor type 6 (E.C.3.1.3.48)
Authors:Yang, J., Liu, L., He, D., Song, X., Liang, X., Zhao, Z.J., Zhou, G.W.
Deposit date:2005-09-20
Release date:2005-10-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 278, 2003
2LR7
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CATHELICIDIN-PY
Descriptor:Cathelicidin-PY
Authors:Yang, J.
Deposit date:2012-03-27
Release date:2013-03-27
Method:SOLUTION NMR
Cite:Structure of Cathelicidin-PY
To be Published
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