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1A5T
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BU of 1a5t by Molmil
CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III
Descriptor: DELTA PRIME, ZINC ION
Authors:Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
1JQL
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BU of 1jql by Molmil
Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of beta-delta (1-140)
Descriptor: DNA Polymerase III, BETA CHAIN, DELTA SUBUNIT
Authors:Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J.
Deposit date:2001-08-07
Release date:2001-09-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
1JQJ
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BU of 1jqj by Molmil
Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of the beta-delta complex
Descriptor: DNA polymerase III, beta chain, delta subunit
Authors:Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J.
Deposit date:2001-08-07
Release date:2001-11-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
8UNF
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BU of 8unf by Molmil
Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ...
Authors:Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J.
Deposit date:2023-10-18
Release date:2023-12-13
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 2024
8UNH
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BU of 8unh by Molmil
Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ...
Authors:Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J.
Deposit date:2023-10-19
Release date:2023-12-13
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 2024
1XXI
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BU of 1xxi by Molmil
ADP Bound E. coli Clamp Loader Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, DNA polymerase III, ...
Authors:Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
Deposit date:2004-11-05
Release date:2004-12-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
1XXH
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BU of 1xxh by Molmil
ATPgS Bound E. Coli Clamp Loader Complex
Descriptor: DNA polymerase III subunit gamma, DNA polymerase III, delta prime subunit, ...
Authors:Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
Deposit date:2004-11-05
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
1NJF
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BU of 1njf by Molmil
Nucleotide bound form of an isolated E. coli clamp loader gamma subunit
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
Deposit date:2002-12-30
Release date:2003-04-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit
Structure, 11, 2003
1SXJ
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BU of 1sxj by Molmil
Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ...
Authors:Bowman, G.D, O'Donnell, M, Kuriyan, J.
Deposit date:2004-03-30
Release date:2004-06-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Nature, 429, 2004
1EQN
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BU of 1eqn by Molmil
E.COLI PRIMASE CATALYTIC CORE
Descriptor: DNA PRIMASE
Authors:Podobnik, M, McInerney, P, O'Donnell, M, Kuriyan, J.
Deposit date:2000-04-05
Release date:2000-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.
J.Mol.Biol., 300, 2000
2HNH
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BU of 2hnh by Molmil
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III
Descriptor: DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Meindert, M.H, Georgescu, R.E, Lee, S, O'Donnell, M, Kuriyan, J.
Deposit date:2006-07-12
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
2HQA
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BU of 2hqa by Molmil
Crystal structure of the catalytic alpha subunit of E. Coli replicative DNA polymerase III
Descriptor: DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Lamers, M.H, Georgescu, R.E, Lee, S.G, O'Donnell, M, Kuriyan, J.
Deposit date:2006-07-18
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
1NJG
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BU of 1njg by Molmil
Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit
Descriptor: DNA polymerase III subunit gamma, SULFATE ION, ZINC ION
Authors:Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
Deposit date:2002-12-30
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit
Structure, 11, 2003
1JR3
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BU of 1jr3 by Molmil
Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III
Descriptor: DNA polymerase III subunit gamma, DNA polymerase III, delta subunit, ...
Authors:Jeruzalmi, D, O'Donnell, M, Kuriyan, J.
Deposit date:2001-08-10
Release date:2001-09-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 106, 2001
2AVT
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BU of 2avt by Molmil
Crystal structure of the beta subunit from DNA polymerase of Streptococcus pyogenes
Descriptor: DNA polymerase III beta subunit
Authors:Argiriadi, M.A, Goedken, E.R, Bruck, I, O'donnell, M, Kuriyan, J.
Deposit date:2005-08-30
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium.
Bmc Struct.Biol., 6, 2006
3BEP
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BU of 3bep by Molmil
Structure of a sliding clamp on DNA
Descriptor: 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ...
Authors:Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2007-11-19
Release date:2008-01-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of a sliding clamp on DNA
Cell(Cambridge,Mass.), 132, 2008
1EM8
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BU of 1em8 by Molmil
Crystal structure of chi and psi subunit heterodimer from DNA POL III
Descriptor: DNA POLYMERASE III CHI SUBUNIT, DNA POLYMERASE III PSI SUBUNIT
Authors:Gulbis, J.M, Finkelstein, J, O'Donnell, M, Kuriyan, J.
Deposit date:2000-03-16
Release date:2003-08-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the chi:psi sub-assembly of the Escherichia coli DNA polymerase clamp-loader complex.
Eur.J.Biochem., 271, 2004
3D1F
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BU of 3d1f by Molmil
Crystal structure of E. coli sliding clamp (beta) bound to a polymerase III peptide
Descriptor: 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, DI(HYDROXYETHYL)ETHER, DNA polymerase III subunit beta, ...
Authors:Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3D1G
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BU of 3d1g by Molmil
Structure of a small molecule inhibitor bound to a DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid
Authors:Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3D1E
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BU of 3d1e by Molmil
Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide
Descriptor: DNA polymerase III subunit beta, decamer from polymerase II C-terminal
Authors:Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3U5Z
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BU of 3u5z by Molmil
Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
4JOM
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BU of 4jom by Molmil
Structure of E. coli Pol III 3mPHP mutant
Descriptor: DNA polymerase III subunit alpha, GLYCEROL, PHOSPHATE ION, ...
Authors:Barros, T, Guenther, J, Kelch, B, Anaya, J, Prabhakar, A, O'Donnell, M, Kuriyan, J, Lamers, M.H.
Deposit date:2013-03-18
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structural role for the PHP domain in E. coli DNA polymerase III.
Bmc Struct.Biol., 13, 2013
1CZD
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BU of 1czd by Molmil
CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4
Descriptor: DNA POLYMERASE ACCESSORY PROTEIN G45
Authors:Moarefi, I, Jeruzalmi, D, Turner, J, O'Donnell, M, Kuriyan, J.
Deposit date:1999-09-02
Release date:2000-03-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage.
J.Mol.Biol., 296, 2000
3U60
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BU of 3u60 by Molmil
Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
3U61
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Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011

 

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