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1HKX
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BU of 1hkx by Molmil
Crystal structure of calcium/calmodulin-dependent protein kinase
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN, CHLORIDE ION, ...
Authors:Hoelz, A, Nairn, A.C, Kuriyan, J.
Deposit date:2003-03-12
Release date:2003-06-02
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of a Tetradecameric Assembly of the Association Domain of Ca2+/Calmodulin-Dependent Kinase II
Mol.Cell, 11, 2003
2DF6
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BU of 2df6 by Molmil
Crystal Structure of the SH3 Domain of betaPIX in Complex with a High Affinity Peptide from PAK2
Descriptor: 18-mer from PAK2, Rho guanine nucleotide exchange factor 7
Authors:Hoelz, A.
Deposit date:2006-02-25
Release date:2006-04-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of the SH3 Domain of betaPIX in Complex with a High Affinity Peptide from PAK2
J.Mol.Biol., 358, 2006
2G6F
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BU of 2g6f by Molmil
Crystal Structure of the SH3 Domain of betaPIX in Complex with a High Affinity Peptide from PAK2
Descriptor: COBALT HEXAMMINE(III), Rho guanine nucleotide exchange factor 7
Authors:Hoelz, A.
Deposit date:2006-02-24
Release date:2006-04-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Crystal Structure of the SH3 Domain of betaPIX in Complex with a High Affinity Peptide from PAK2
J.Mol.Biol., 358, 2006
3MMY
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BU of 3mmy by Molmil
Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclear pore complex protein Nup98, mRNA export factor
Authors:Hoelz, A, Ren, Y.
Deposit date:2010-04-20
Release date:2010-06-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MV3
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BU of 3mv3 by Molmil
Crystal Structure of a-COP in Complex with e-COP
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon
Authors:Hoelz, A, Hsia, K.C.
Deposit date:2010-05-03
Release date:2010-06-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MV2
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BU of 3mv2 by Molmil
Crystal Structure of a-COP in Complex with e-COP
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon
Authors:Hoelz, A, Hsia, K.C.
Deposit date:2010-05-03
Release date:2010-06-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat.
Proc.Natl.Acad.Sci.USA, 107, 2010
3BG1
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BU of 3bg1 by Molmil
Architecture of a Coat for the Nuclear Pore Membrane
Descriptor: Nucleoporin NUP145, Protein SEC13 homolog
Authors:Hoelz, A.
Deposit date:2007-11-23
Release date:2008-01-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Architecture of a coat for the nuclear pore membrane.
Cell(Cambridge,Mass.), 131, 2007
3BG0
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BU of 3bg0 by Molmil
Architecture of a Coat for the Nuclear Pore Membrane
Descriptor: Nucleoporin NUP145, Protein SEC13 homolog
Authors:Hoelz, A.
Deposit date:2007-11-23
Release date:2008-01-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Architecture of a coat for the nuclear pore membrane.
Cell(Cambridge,Mass.), 131, 2007
3CZ7
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BU of 3cz7 by Molmil
Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109
Descriptor: ACETYL COENZYME *A, Regulator of Ty1 transposition protein 109
Authors:Hoelz, A, Stavropoulos, P.
Deposit date:2008-04-28
Release date:2008-09-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for the autoregulation of the protein acetyl transferase Rtt109
Proc.Natl.Acad.Sci.Usa, 105, 2008
4GA1
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BU of 4ga1 by Molmil
Structure of the N-terminal domain of Nup358
Descriptor: E3 SUMO-PROTEIN LIGASE RANBP2
Authors:Hoelz, A, Kassube, S.A, Lin, D.H, Stuwe, T.
Deposit date:2012-07-24
Release date:2012-09-26
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of the N-terminal domain of Nup358/RanBP2.
J.Mol.Biol., 423, 2012
7TBL
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BU of 7tbl by Molmil
Composite structure of the human nuclear pore complex (NPC) cytoplasmic face generated with a 12A cryo-ET map of the purified HeLa cell NPC
Descriptor: DDX19, ELYS, GLE1, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-12-22
Release date:2022-06-22
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
6UY1
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BU of 6uy1 by Molmil
Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution
Descriptor: MAGNESIUM ION, Nuclear protein STH1/NPS1
Authors:Stavropoulos, P, Hoelz, A.
Deposit date:2019-11-09
Release date:2019-12-04
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of the Sth1 bromodomain from Saccharomyces cerevisiae at 2.2 Angstrom resolution
To Be Published
7TBM
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BU of 7tbm by Molmil
Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC
Descriptor: DDX19, NUP107 CTD, NUP107 NTD, ...
Authors:Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
Deposit date:2021-12-22
Release date:2022-06-15
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (37 Å)
Cite:Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7TBJ
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BU of 7tbj by Molmil
Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC
Descriptor: NUP107 CTD, NUP107 NTD, NUP133, ...
Authors:Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
Deposit date:2021-12-22
Release date:2022-06-22
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
3TKN
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BU of 3tkn by Molmil
Structure of the Nup82-Nup159-Nup98 heterotrimer
Descriptor: Nucleoporin 98, Nucleoporin NUP159, Nucleoporin NUP82
Authors:Stuwe, T.T, Hoelz, A.
Deposit date:2011-08-28
Release date:2012-04-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular basis for the anchoring of proto-oncoprotein nup98 to the cytoplasmic face of the nuclear pore complex.
J.Mol.Biol., 419, 2012
2H94
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BU of 2h94 by Molmil
Crystal Structure and Mechanism of human Lysine-Specific Demethylase-1
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1, MERCURY (II) ION
Authors:Stavropoulos, P, Blobel, G, Hoelz, A.
Deposit date:2006-06-08
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and mechanism of human lysine-specific demethylase-1.
Nat.Struct.Mol.Biol., 13, 2006
7TBK
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BU of 7tbk by Molmil
Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC
Descriptor: NUP107 CTD, NUP107 NTD, NUP133, ...
Authors:Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
Deposit date:2021-12-22
Release date:2022-06-15
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (37 Å)
Cite:Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7TBI
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BU of 7tbi by Molmil
Composite structure of the S. cerevisiae nuclear pore complex (NPC)
Descriptor: Dyn2, Nic96 R1, Nic96 R2, ...
Authors:Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
Deposit date:2021-12-22
Release date:2022-06-15
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (25 Å)
Cite:Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
3IKO
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BU of 3iko by Molmil
Crystal structure of the heterotrimeric Sec13-Nup145C-Nup84 nucleoporin complex
Descriptor: Nucleoporin NUP145C, Nucleoporin NUP84, Protein transport protein SEC13
Authors:Nagy, V, Hsia, K.-C, Debler, E.W, Davenport, A, Blobel, G, Hoelz, A.
Deposit date:2009-08-06
Release date:2009-10-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of a trimeric nucleoporin complex reveals alternate oligomerization states.
Proc.Natl.Acad.Sci.USA, 106, 2009
1NVV
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BU of 1nvv by Molmil
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
Deposit date:2003-02-04
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
2OIT
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BU of 2oit by Molmil
Crystal Structure of the N-terminal Domain of the Human Proto-oncogene Nup214/CAN
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoporin 214kDa
Authors:Napetschnig, J, Blobel, G, Hoelz, A.
Deposit date:2007-01-11
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OSZ
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BU of 2osz by Molmil
Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding
Descriptor: Nucleoporin p58/p45
Authors:Melcak, I, Hoelz, A, Blobel, G.
Deposit date:2007-02-06
Release date:2007-04-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding.
Science, 315, 2007
5TQB
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BU of 5tqb by Molmil
Crystal structure of assembly chaperone of ribosomal protein L4 (Acl4) in complex with ribosomal protein L4 (RpL4)
Descriptor: 1,2-ETHANEDIOL, 60S ribosomal protein L4-like protein, Assembly chaperone of ribosomal protein L4 (Acl4), ...
Authors:Huber, F.M, Hoelz, A.
Deposit date:2016-10-23
Release date:2017-02-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for protection of ribosomal protein L4 from cellular degradation.
Nat Commun, 8, 2017
5TQC
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BU of 5tqc by Molmil
Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4)
Descriptor: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1
Authors:Huber, F.M, Hoelz, A.
Deposit date:2016-10-23
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis for protection of ribosomal protein L4 from cellular degradation.
Nat Commun, 8, 2017
5VDC
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BU of 5vdc by Molmil
Crystal structure of the human DPF2 tandem PHD finger domain
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, ZINC ION, ...
Authors:Huber, F.M, Davenport, A.M, Hoelz, A.
Deposit date:2017-04-01
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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