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1HMY
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BU of 1hmy by Molmil
CRYSTAL STRUCTURE OF THE HHAI DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE
Descriptor: HaeIII METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Cheng, X.
Deposit date:1993-08-05
Release date:1993-10-31
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.
Cell(Cambridge,Mass.), 74, 1993
1LBA
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BU of 1lba by Molmil
THE STRUCTURE OF BACTERIOPHAGE T7 LYSOZYME, A ZINC AMIDASE AND AN INHIBITOR OF T7 RNA POLYMERASE
Descriptor: T7 LYSOZYME, ZINC ION
Authors:Cheng, X.
Deposit date:1993-12-22
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of bacteriophage T7 lysozyme, a zinc amidase and an inhibitor of T7 RNA polymerase.
Proc.Natl.Acad.Sci.USA, 91, 1994
1PVI
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BU of 1pvi by Molmil
STRUCTURE OF PVUII ENDONUCLEASE WITH COGNATE DNA
Descriptor: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII (E.C.3.1.21.4))
Authors:Cheng, X, Balendiran, K, Schildkraut, I, Anderson, J.E.
Deposit date:1994-11-16
Release date:1995-02-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of PvuII endonuclease with cognate DNA.
EMBO J., 13, 1994
5CX3
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BU of 5cx3 by Molmil
Crystal structure of FYCO1 LIR in complex with LC3A
Descriptor: FYVE and coiled-coil domain-containing protein 1, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3A
Authors:Cheng, X, Pan, L.
Deposit date:2015-07-28
Release date:2016-08-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins.
Autophagy, 12, 2016
5MHT
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BU of 5mht by Molmil
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH HEMIMETHYLATED DNA AND ADOHCY
Descriptor: DNA (5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ...
Authors:Cheng, X.
Deposit date:1996-10-22
Release date:1997-07-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase.
J.Mol.Biol., 263, 1996
1MHT
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BU of 1mht by Molmil
COVALENT TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE, DNA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor: DNA (5'-D(*TP*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ...
Authors:Cheng, X.
Deposit date:1994-12-08
Release date:1995-06-03
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:HhaI methyltransferase flips its target base out of the DNA helix.
Cell(Cambridge,Mass.), 76, 1994
2PVC
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BU of 2pvc by Molmil
DNMT3L recognizes unmethylated histone H3 lysine 4
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, Histone H3 peptide, ZINC ION
Authors:Cheng, X.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.
Nature, 448, 2007
2PV0
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BU of 2pv0 by Molmil
DNA methyltransferase 3 like protein (DNMT3L)
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, ZINC ION
Authors:Cheng, X.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.
Nature, 448, 2007
4MHT
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BU of 4mht by Molmil
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY
Descriptor: DNA (5'-D(*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ...
Authors:Cheng, X.
Deposit date:1996-07-24
Release date:1997-01-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
J.Mol.Biol., 261, 1996
3CBP
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BU of 3cbp by Molmil
Set7/9-ER-Sinefungin complex
Descriptor: BETA-MERCAPTOETHANOL, Estrogen receptor, GLYCEROL, ...
Authors:Cheng, X, Jia, D.
Deposit date:2008-02-22
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol.Cell, 30, 2008
3CBO
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BU of 3cbo by Molmil
SET7/9-ER-AdoHcy complex
Descriptor: BETA-MERCAPTOETHANOL, Estrogen receptor, GLYCEROL, ...
Authors:Cheng, X, Jia, D.
Deposit date:2008-02-22
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol.Cell, 30, 2008
3CBM
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BU of 3cbm by Molmil
SET7/9-ER-AdoMet complex
Descriptor: BETA-MERCAPTOETHANOL, Estrogen receptor, Histone-lysine N-methyltransferase SETD7, ...
Authors:Cheng, X, Jia, D.
Deposit date:2008-02-22
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol.Cell, 30, 2008
2M2D
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BU of 2m2d by Molmil
Human programmed cell death 1 receptor
Descriptor: Programmed cell death protein 1
Authors:Veverka, V, Cheng, X, Waters, L.C, Muskett, F.W, Morgan, S, Lesley, A, Griffiths, M, Stubberfield, C, Griffin, R, Henry, A.J, Robinson, M.K, Jansson, A, Ladbury, J.E, Ikemizu, S, Davis, S.J, Carr, M.D.
Deposit date:2012-12-18
Release date:2013-02-27
Last modified:2013-05-15
Method:SOLUTION NMR
Cite:Structure and interactions of the human programmed cell death 1 receptor.
J.Biol.Chem., 288, 2013
2MB5
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BU of 2mb5 by Molmil
HYDRATION IN PROTEIN CRYSTALS. A NEUTRON DIFFRACTION ANALYSIS OF CARBONMONOXYMYOGLOBIN
Descriptor: AMMONIUM CATION WITH D, CARBON MONOXIDE, MYOGLOBIN, ...
Authors:Schoenborn, B.P, Cheng, X.
Deposit date:1989-10-11
Release date:1991-04-15
Last modified:2024-02-21
Method:NEUTRON DIFFRACTION (1.8 Å)
Cite:Hydration in Protein Crystals. A Neutron Diffraction Analysis of Carbonmonoxymyoglobin
Acta Crystallogr.,Sect.B, 46, 1990
5X56
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BU of 5x56 by Molmil
Crystal structure of PSB27 from Arabidopsis thaliana
Descriptor: Photosystem II repair protein PSB27-H1, chloroplastic
Authors:Liu, J, Cheng, X.
Deposit date:2017-02-15
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of Psb27 from Arabidopsis thaliana determined at a resolution of 1.85 angstrom.
Photosyn. Res., 136, 2018
6IR8
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BU of 6ir8 by Molmil
Rice WRKY/DNA complex
Descriptor: DNA (5'-D(P*GP*AP*TP*AP*TP*TP*TP*GP*AP*CP*CP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*GP*GP*TP*CP*AP*AP*AP*TP*AP*TP*C)-3'), OsWRKY45, ...
Authors:Liu, J, Cheng, X, Wang, D.
Deposit date:2018-11-12
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain.
Nucleic Acids Res., 47, 2019
6MHT
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BU of 6mht by Molmil
TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET
Descriptor: CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), ...
Authors:Cheng, X.
Deposit date:1998-08-05
Release date:1998-08-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.
Nucleic Acids Res., 25, 1997
1CSN
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BU of 1csn by Molmil
BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CASEIN KINASE-1, MAGNESIUM ION, ...
Authors:Xu, R.-M, Cheng, X.
Deposit date:1995-04-25
Release date:1995-07-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of casein kinase-1, a phosphate-directed protein kinase.
EMBO J., 14, 1995
6DQ4
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BU of 6dq4 by Molmil
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR GSK-J1
Descriptor: 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2018-06-10
Release date:2018-11-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.392 Å)
Cite:Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.
J. Med. Chem., 61, 2018
6DQ9
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BU of 6dq9 by Molmil
Linked KDM5A JMJ Domain Bound to the Covalent Inhibitor N69 i.e. [2-((3-acrylamidophenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylic acid]
Descriptor: 1,2-ETHANEDIOL, 2-{(R)-[3-(acryloylamino)phenyl][2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid, DIMETHYL SULFOXIDE, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2018-06-10
Release date:2018-11-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.748 Å)
Cite:Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.
J. Med. Chem., 61, 2018
6DQ5
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BU of 6dq5 by Molmil
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N43 i.e. 3-((6-(4-acryloyl-1,4-diazepan-1-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid
Descriptor: Linked KDM5A Jmj Domain, MANGANESE (II) ION, N-[6-(4-acryloyl-1,4-diazepan-1-yl)-2-(pyridin-2-yl)pyrimidin-4-yl]-beta-alanine
Authors:Horton, J.R, Cheng, X.
Deposit date:2018-06-10
Release date:2018-11-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.
J. Med. Chem., 61, 2018
6DQE
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BU of 6dqe by Molmil
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N67 i.e. 2-(5-phenyl-4-(phenyl(2-(piperidin-1-yl)ethoxy)methyl)-1H-pyrazol-1-yl)isonicotinic acid
Descriptor: 2-(5-phenyl-4-{(R)-phenyl[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrazol-1-yl)pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2018-06-10
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.689 Å)
Cite:To be determined
To Be Published
6DQD
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BU of 6dqd by Molmil
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N53 i.e. 2-(5-([1,1'-biphenyl]-3-yl)-4-(1-(2-(piperidin-1-yl)ethoxy)ethyl)-1H-pyrazol-1-yl)isonicotinic acid
Descriptor: 2-[5-([1,1'-biphenyl]-3-yl)-4-{(1S)-1-[2-(piperidin-1-yl)ethoxy]ethyl}-1H-pyrazol-1-yl]pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2018-06-10
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.987 Å)
Cite:To be determined
To Be Published
1BOO
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BU of 1boo by Molmil
PVUII DNA METHYLTRANSFERASE (CYTOSINE-N4-SPECIFIC)
Descriptor: PROTEIN (N-4 CYTOSINE-SPECIFIC METHYLTRANSFERASE PVU II), S-ADENOSYL-L-HOMOCYSTEINE
Authors:Gong, W, O'Gara, M, Blumenthal, R.M, Cheng, X.
Deposit date:1998-07-31
Release date:1998-08-12
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment.
Nucleic Acids Res., 25, 1997
4R28
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BU of 4r28 by Molmil
MspJI Restriction Endonuclease in Complex with 27-mer Oligonucleotide
Descriptor: DNA (25-MER), DNA (26-MER), Restriction endonuclease
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-08-10
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.055 Å)
Cite:Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.
Nucleic Acids Res., 42, 2014

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