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2AKP
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BU of 2akp by Molmil
Hsp90 Delta24-N210 mutant
Descriptor: ATP-dependent molecular chaperone HSP82
Authors:Richter, K, Moser, S, Hagn, F, Friedrich, R, Hainzl, O, Heller, M, Schlee, S, Kessler, H, Reinstein, J, Buchner, J.
Deposit date:2005-08-03
Release date:2006-01-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Intrinsic inhibition of the Hsp90 ATPase activity.
J.Biol.Chem., 281, 2006
2YGD
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BU of 2ygd by Molmil
Molecular architectures of the 24meric eye lens chaperone alphaB- crystallin elucidated by a triple hybrid approach
Descriptor: ALPHA-CRYSTALLIN B CHAIN
Authors:Braun, N, Zacharias, M, Peschek, J, Kastenmueller, A, Zou, J, Hanzlik, M, Haslbeck, M, Rappsilber, J, Buchner, J, Weinkauf, S.
Deposit date:2011-04-13
Release date:2011-12-07
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Multiple Molecular Architectures of the Eye Lens Chaperone Alpha Beta-Crystallin Elucidated by a Triple Hybrid Approach
Proc.Natl.Acad.Sci.USA, 108, 2011
4Q9C
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BU of 4q9c by Molmil
IgNAR antibody domain C3
Descriptor: CHLORIDE ION, Novel antigen receptor, SODIUM ION, ...
Authors:Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J.
Deposit date:2014-04-30
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q97
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BU of 4q97 by Molmil
IgNAR antibody domain C1
Descriptor: Novel antigen receptor
Authors:Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J.
Deposit date:2014-04-29
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
1CQK
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BU of 1cqk by Molmil
CRYSTAL STRUCTURE OF THE CH3 DOMAIN FROM THE MAK33 ANTIBODY
Descriptor: CH3 DOMAIN OF MAK33 ANTIBODY
Authors:Thies, M.J, Mayer, J, Augustine, J.G, Frederick, C.A, Lilie, H, Buchner, J.
Deposit date:1999-08-06
Release date:1999-09-11
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Folding and association of the antibody domain CH3: prolyl isomerization preceeds dimerization.
J.Mol.Biol., 293, 1999
3UQ3
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BU of 3uq3 by Molmil
TPR2AB-domain:pHSP90-complex of yeast Sti1
Descriptor: Heat shock protein, Heat shock protein STI1
Authors:Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J.
Deposit date:2011-11-19
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
4Q9B
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BU of 4q9b by Molmil
IgNAR antibody domain C2
Descriptor: Novel antigen receptor
Authors:Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J.
Deposit date:2014-04-30
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
7OA6
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BU of 7oa6 by Molmil
Pseudo-atomic model for Hsp26 residues 63 to 214. Please be advised that the target map is not of sufficient resolution to unambiguously position backbone or side chain atoms. This model represents a likely fit.
Descriptor: Heat shock protein 26
Authors:Muehlhofer, M, Peters, C, Kriehuber, T, Kreuzeder, M, Kazman, P, Rodina, N, Reif, B, Haslbeck, M, Weinkauf, S, Buchner, J.
Deposit date:2021-04-19
Release date:2021-11-24
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble.
Nat Commun, 12, 2021
7PE3
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BU of 7pe3 by Molmil
Pseudo-atomic model of the tetrahedral 24mer of Hsp17 from Caenorhabditis elegans
Descriptor: SHSP domain-containing protein
Authors:Rossa, B, Weinkauf, S, Buchner, J.
Deposit date:2021-08-09
Release date:2022-12-14
Last modified:2023-01-04
Method:ELECTRON MICROSCOPY (6.49 Å)
Cite:The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions.
J.Biol.Chem., 299, 2022
4BA8
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BU of 4ba8 by Molmil
High resolution NMR structure of the C mu3 domain from IgM
Descriptor: IG MU CHAIN C REGION SECRETED FORM
Authors:Mueller, R, Kern, T, Graewert, M.A, Madl, T, Peschek, J, Groll, M, Sattler, M, Buchner, J.
Deposit date:2012-09-12
Release date:2013-06-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:High Resolution Structures of the Igm Fc Domains Reveal Principles of its Hexamer Formation
Proc.Natl.Acad.Sci.USA, 110, 2013
6T1R
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BU of 6t1r by Molmil
Pseudo-atomic model of a 16-mer assembly of reduced recombinant human alphaA-crystallin (non domain swapped configuration)
Descriptor: Alpha-crystallin A chain
Authors:Peters, C, Kaiser, C.J.O, Weinkauf, S, Zacharias, M, Buchner, J.
Deposit date:2019-10-05
Release date:2019-12-11
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:The structure and oxidation of the eye lens chaperone alpha A-crystallin.
Nat.Struct.Mol.Biol., 26, 2019
3HKF
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BU of 3hkf by Molmil
Murine unglycosylated IgG Fc fragment
Descriptor: CHLORIDE ION, Igh protein, MAGNESIUM ION
Authors:Feige, M.J, Nath, S, Catharino, S.R, Weinfurtner, D, Steinbacher, S, Buchner, J.
Deposit date:2009-05-23
Release date:2009-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the murine unglycosylated IgG1 Fc fragment
J.Mol.Biol., 391, 2009
1FH5
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BU of 1fh5 by Molmil
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF THE MONOCLONAL ANTIBODY MAK33
Descriptor: MONOCLONAL ANTIBODY MAK33
Authors:Augustine, J.G, de la Calle, A, Knarr, G, Buchner, J, Frederick, C.A.
Deposit date:2000-07-31
Release date:2000-09-13
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip.
J.Biol.Chem., 276, 2001
4YE0
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BU of 4ye0 by Molmil
Stress-induced protein 1 truncation mutant (43 - 140) from Caenorhabditis elegans
Descriptor: SULFATE ION, Stress-induced protein 1
Authors:Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J.
Deposit date:2015-02-23
Release date:2015-06-10
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.
Mol.Cell, 58, 2015
4YDZ
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BU of 4ydz by Molmil
Stress-induced protein 1 from Caenorhabditis elegans
Descriptor: Stress-induced protein 1
Authors:Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J.
Deposit date:2015-02-23
Release date:2015-06-10
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.
Mol.Cell, 58, 2015
2LLV
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BU of 2llv by Molmil
Solution structure of the yeast Sti1 DP1 domain
Descriptor: Heat shock protein STI1
Authors:Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J.
Deposit date:2011-11-17
Release date:2012-01-25
Last modified:2012-04-04
Method:SOLUTION NMR
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
2LLW
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BU of 2llw by Molmil
Solution structure of the yeast Sti1 DP2 domain
Descriptor: Heat shock protein STI1
Authors:Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J.
Deposit date:2011-11-17
Release date:2012-01-25
Last modified:2012-04-04
Method:SOLUTION NMR
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
4JVW
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BU of 4jvw by Molmil
IgM C4-domain from mouse
Descriptor: Ig mu chain C region secreted form
Authors:Mueller, R, Graewert, A.M, Kern, T, Madl, T, Peschek, J, Sattler, M, Groll, M, Buchner, J.
Deposit date:2013-03-26
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JVU
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BU of 4jvu by Molmil
IgM C2-domain from mouse
Descriptor: Ig mu chain C region membrane-bound form
Authors:Mueller, R, Graewert, A.M, Kern, T, Madl, T, Peschek, J, Sattler, M, Groll, M, Buchner, J.
Deposit date:2013-03-26
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6SM2
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BU of 6sm2 by Molmil
Mutant immunoglobulin light chain causing amyloidosis (Pat-1)
Descriptor: Pat-1
Authors:Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J.
Deposit date:2019-08-21
Release date:2020-03-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
Elife, 9, 2020
6SM1
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BU of 6sm1 by Molmil
Wild type immunoglobulin light chain (WT-1)
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Immunoglobulin lambda variable 2-14, ...
Authors:Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J.
Deposit date:2019-08-21
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
Elife, 9, 2020
2H50
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BU of 2h50 by Molmil
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Descriptor: small heat shock protein Hsp26
Authors:White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (10.8 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2H53
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BU of 2h53 by Molmil
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Descriptor: small heat shock protein Hsp26
Authors:White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
4FEI
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BU of 4fei by Molmil
Hsp17.7 from Deinococcus radiodurans
Descriptor: Heat shock protein-related protein
Authors:Bepperling, A, Alte, F, Kriehuber, T, Braun, N, Weinkauf, S, Groll, M, Haslbeck, M, Buchner, J.
Deposit date:2012-05-30
Release date:2012-12-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Alternative bacterial two-component small heat shock protein systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
2MKL
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BU of 2mkl by Molmil
Solution structure of the fourth constant immunoglobulin domain of nurse shark IgNAR
Descriptor: Novel antigen receptor
Authors:Hennig, J, Sattler, M.
Deposit date:2014-02-10
Release date:2014-07-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014

 

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