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1AQM
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BU of 1aqm by Molmil
ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS COMPLEXED WITH TRIS
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-AMYLASE, CALCIUM ION, ...
Authors:Aghajari, N, Haser, R.
Deposit date:1997-07-31
Release date:1999-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
1AQH
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BU of 1aqh by Molmil
ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS
Descriptor: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
Authors:Aghajari, N, Haser, R.
Deposit date:1997-07-30
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
1B0I
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BU of 1b0i by Molmil
ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS
Descriptor: CALCIUM ION, CHLORIDE ION, PROTEIN (ALPHA-AMYLASE)
Authors:Aghajari, N, Haser, R.
Deposit date:1998-11-10
Release date:1999-11-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the psychrophilic Alteromonas haloplanctis alpha-amylase give insights into cold adaptation at a molecular level.
Structure, 6, 1998
1G94
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BU of 1g94 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS IN COMPLEX WITH A HEPTA-SACCHARIDE AND A TRIS MOLECULE
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Aghajari, N, Roth, M, Haser, R.
Deposit date:2000-11-22
Release date:2001-12-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.
Biochemistry, 41, 2002
1G9H
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BU of 1g9h by Molmil
TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA-AMYLASE, COMII (PSEUDO TRI-SACCHARIDE FROM BAYER) AND TRIS (2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose, ALPHA-AMYLASE, ...
Authors:Aghajari, N, Roth, M, Haser, R.
Deposit date:2000-11-23
Release date:2002-06-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.
Biochemistry, 41, 2002
1JD9
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BU of 1jd9 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE MUTANT K300Q OF PSEUDOALTEROMONAS HALOPLANCTIS ALPHA-AMYLASE
Descriptor: ALPHA-AMYLASE, CALCIUM ION
Authors:Aghajari, N, Haser, R.
Deposit date:2001-06-13
Release date:2002-09-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of alpha-amylase activation by chloride
PROTEIN SCI., 11, 2002
1JD7
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BU of 1jd7 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE MUTANT K300R OF PSEUDOALTEROMONAS HALOPLANCTIS ALPHA-AMYLASE
Descriptor: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
Authors:Aghajari, N, Haser, R.
Deposit date:2001-06-13
Release date:2002-09-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of alpha-amylase activation by chloride
PROTEIN SCI., 11, 2002
1G9K
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BU of 1g9k by Molmil
CRYSTAL STRUCTURE OF A PSYCHROPHILIC ALKALINE PROTEASE FROM PSEUDOMONAS TAC II 18
Descriptor: CALCIUM ION, SERRALYSIN, SULFATE ION, ...
Authors:Aghajari, N, Haser, R.
Deposit date:2000-11-24
Release date:2003-02-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases
Proteins, 50, 2003
1L0P
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BU of 1l0p by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS AND NITRATE
Descriptor: ALPHA-AMYLASE, CALCIUM ION, NITRATE ION
Authors:Aghajari, N, Haser, R.
Deposit date:2002-02-12
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of alpha-amylase activation by chloride.
Protein Sci., 11, 2002
1KXH
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BU of 1kxh by Molmil
Crystal structure of the complex between an inactive mutant of psychrophilic alpha-amylase (D174N) and acarbose
Descriptor: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Aghajari, N, Haser, R.
Deposit date:2002-01-31
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase.
Biochemistry, 41
5CR7
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BU of 5cr7 by Molmil
Human cytosolic 5'-nucleotidase II in complex with N-(9H-Purin-6-yl)-3-(3-pyrrol-1-ylphenyl)benzamide
Descriptor: ACETATE ION, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
Authors:Aghajari, N, Preeti, P.
Deposit date:2015-07-22
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach.
J.Med.Chem., 58, 2015
8OR6
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BU of 8or6 by Molmil
Crystal structure of Drosophila melanogaster alpha-amylase
Descriptor: Alpha-amylase A, CHLORIDE ION, STRONTIUM ION
Authors:Aghajari, N, Haser, R.
Deposit date:2023-04-13
Release date:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
8ORP
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BU of 8orp by Molmil
Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose
Descriptor: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
Authors:Aghajari, N, Haser, R.
Deposit date:2023-04-16
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
8QZK
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BU of 8qzk by Molmil
Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4 Hexagonal form
Descriptor: ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE
Authors:Aghajari, N, Hansen, A.L, Thiesen, F.F, Crehuet, R, Marcos, E, Willemoes, M.
Deposit date:2023-10-27
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
8QYE
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BU of 8qye by Molmil
Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4
Descriptor: 1,2-ETHANEDIOL, ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE
Authors:Aghajari, N.
Deposit date:2023-10-25
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
3BSH
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BU of 3bsh by Molmil
Barley alpha-amylase isozyme 1 (AMY1) double mutant Y105A/Y380A in complex with inhibitor acarbose
Descriptor: Alpha-amylase type A isozyme, CALCIUM ION, beta-D-glucopyranose
Authors:Aghajari, N, Robert, X, Haser, R.
Deposit date:2007-12-24
Release date:2008-08-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multi-site substrate binding and interplay in barley alpha-amylase 1
Febs Lett., 582, 2008
3BSG
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BU of 3bsg by Molmil
Barley alpha-amylase isozyme 1 (AMY1) H395A mutant
Descriptor: Alpha-amylase type A isozyme, CALCIUM ION
Authors:Aghajari, N, Robert, X, Haser, R.
Deposit date:2007-12-24
Release date:2008-08-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Multi-site substrate binding and interplay in barley alpha-amylase 1
Febs Lett., 582, 2008
2QPS
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BU of 2qps by Molmil
"Sugar tongs" mutant Y380A in complex with acarbose
Descriptor: Alpha-amylase type A isozyme, CALCIUM ION
Authors:Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
Deposit date:2007-07-25
Release date:2008-02-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
2QPU
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BU of 2qpu by Molmil
Sugar tongs mutant S378P in complex with acarbose
Descriptor: 1,2-ETHANEDIOL, 1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
Authors:Aghajari, N, Jensen, M.H, Tranier, S, Haser, R.
Deposit date:2007-07-25
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The 'pair of sugar tongs' site on the non-catalytic domain C of barley alpha-amylase participates in substrate binding and activity
Febs J., 274, 2007
1H71
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BU of 1h71 by Molmil
Psychrophilic Protease from Pseudoalteromonas 'TAC II 18'
Descriptor: CALCIUM ION, SERRALYSIN, ZINC ION
Authors:Villeret, V, Van Petegem, F, Aghajari, N, Chessa, J.-P, Gerday, C, Haser, R, Van Beeumen, J.
Deposit date:2001-07-02
Release date:2003-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of a Psychrophilic Metalloprotease Reveal New Insights Into Catalysis by Cold-Adapted Proteases
Proteins: Struct.,Funct., Genet., 50, 2003
6FIW
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BU of 6fiw by Molmil
Human cytosolic 5'-nucleotidase II co-crystallized with 10mM Sodium ((4-(3'-((7H-purin-6-yl)carbamoyl)-[1,1'-biphenyl]-3-yl)-1H-imidazol-1-yl) methyl) phosphonate
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Aghajari, N, Preeti, P.
Deposit date:2018-01-19
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FIS
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BU of 6fis by Molmil
Human cytosolic 5'-nucleotidase II soaked with 10mM 7-Benzyloxymethyl-7H-adenine
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Aghajari, N, Preeti, P.
Deposit date:2018-01-19
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FIR
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BU of 6fir by Molmil
Human cytosolic 5'-nucleotidase II soaked with 5mM3-Phenyl-N-(9H-purin-6-yl)benzamide
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Aghajari, N, Preeti, P.
Deposit date:2018-01-19
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FIU
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BU of 6fiu by Molmil
Human cytosolic 5'-nucleotidase II soaked with 10mM 2-(6-([1,1'-Biphenyl]-3-carboxamido)-9H-purin-9-yl)acetic acid
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Aghajari, N, Preeti, P.
Deposit date:2018-01-19
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019
6FXH
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BU of 6fxh by Molmil
Human cytosolic 5'-nucleotidase II soaked with 10mM 3-Phenyl-N-(9H-purin-6-yl)benzamide
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ...
Authors:Aghajari, N, Preeti, P.
Deposit date:2018-03-09
Release date:2019-03-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lead optimization and biological evaluation of fragment-based cN-II inhibitors.
Eur J Med Chem, 168, 2019

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