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2OR1
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BU of 2or1 by Molmil
RECOGNITION OF A DNA OPERATOR BY THE REPRESSOR OF PHAGE 434. A VIEW AT HIGH RESOLUTION
Descriptor: 434 REPRESSOR, DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3')
Authors:Aggarwal, A.K, Rodgers, D.W, Drottar, M, Ptashne, M, Harrison, S.C.
Deposit date:1989-09-05
Release date:1989-09-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of a DNA operator by the repressor of phage 434: a view at high resolution.
Science, 242, 1988
1BAM
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BU of 1bam by Molmil
STRUCTURE OF RESTRICTION ENDONUCLEASE BAMHI PHASED AT 1.95 ANGSTROMS RESOLUTION BY MAD ANALYSIS
Descriptor: ENDONUCLEASE BamH I
Authors:Aggarwal, A.K, Newman, M.
Deposit date:1994-12-28
Release date:1995-02-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of restriction endonuclease bamhi phased at 1.95 A resolution by MAD analysis.
Structure, 2, 1994
1BHM
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BU of 1bhm by Molmil
RESTRICTION ENDONUCLEASE BAMHI COMPLEX WITH DNA
Descriptor: DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), PROTEIN (BAMHI (E.C.3.1.21.4))
Authors:Aggarwal, A.K, Newman, M.
Deposit date:1995-07-12
Release date:1995-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Bam HI endonuclease bound to DNA: partial folding and unfolding on DNA binding.
Science, 269, 1995
2EZV
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BU of 2ezv by Molmil
Crystal structure of tetrameric restriction endonuclease SfiI bound to cognate DNA.
Descriptor: 5'-D(*AP*GP*GP*CP*CP*TP*TP*GP*TP*TP*GP*GP*CP*CP*A)-3', 5'-D(*TP*GP*GP*CP*CP*AP*AP*CP*AP*AP*GP*GP*CP*CP*T)-3', CALCIUM ION, ...
Authors:Aggarwal, A.K, Vanamee, E.S, Viadiu, H.
Deposit date:2005-11-10
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA
Embo J., 24, 2005
2F03
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BU of 2f03 by Molmil
Crystal structure of tetrameric restriction endonuclease SfiI in complex with cognate DNA (partial bound form)
Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*TP*AP*GP*GP*CP*CP*TP*TP*GP*TP*TP*GP*GP*CP*CP*AP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*G*TP*GP*GP*CP*CP*AP*AP*CP*AP*AP*GP*GP*CP*CP*TP*AP*TP*T)-3'), ...
Authors:Aggarwal, A.K, Vanamee, E.S, Viadiu, H
Deposit date:2005-11-11
Release date:2007-01-16
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA.
Embo J., 24, 2005
2R5Y
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BU of 2r5y by Molmil
Structure of Scr/Exd complex bound to a consensus Hox-Exd site
Descriptor: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ...
Authors:Aggarwal, A.K, Passner, J.M, Jain, R.
Deposit date:2007-09-04
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional specificity of a Hox protein mediated by the recognition of minor groove structure
Cell(Cambridge,Mass.), 131, 2007
2R5Z
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BU of 2r5z by Molmil
Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene
Descriptor: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DAP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DTP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ...
Authors:Aggarwal, A.K, Passner, J.M, Jain, R.
Deposit date:2007-09-04
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional specificity of a Hox protein mediated by the recognition of minor groove structure
Cell(Cambridge,Mass.), 131, 2007
1D2I
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BU of 1d2i by Molmil
CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE BGLII COMPLEXED WITH DNA 16-MER
Descriptor: DNA (5'-D(*TP*AP*TP*TP*AP*TP*AP*GP*AP*TP*CP*TP*AP*TP*AP*A)-3'), MAGNESIUM ION, PROTEIN (RESTRICTION ENDONUCLEASE BGLII)
Authors:Lukacs, C.M, Kucera, R, Schildkraut, I, Aggarwal, A.K.
Deposit date:1999-09-23
Release date:2000-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution.
Nat.Struct.Biol., 7, 2000
1DFM
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BU of 1dfm by Molmil
Crystal structure of restriction endonuclease BGLII complexed with DNA 16-mer
Descriptor: CALCIUM ION, DNA (5'-D(*TP*AP*TP*TP*AP*TP*AP*GP*AP*TP*CP*TP*AP*TP*AP*A)-3'), ENDONUCLEASE BGLII
Authors:Lukacs, C.M, Kucera, R, Schildkraut, I, Aggarwal, A.K.
Deposit date:1999-12-06
Release date:2000-02-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution.
Nat.Struct.Biol., 7, 2000
1ESG
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BU of 1esg by Molmil
RESTRICTION ENDONUCLEASE BAMHI BOUND TO A NON-SPECIFIC DNA.
Descriptor: DNA (5'-D(*TP*GP*AP*AP*TP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*AP*TP*TP*CP*A)-3'), TYPE II RESTRICTION ENZYME BAMHI
Authors:Viadiu, H, Aggarwal, A.K.
Deposit date:2000-04-09
Release date:2000-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of BamHI bound to nonspecific DNA: a model for DNA sliding.
Mol.Cell, 5, 2000
1B8I
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BU of 1b8i by Molmil
STRUCTURE OF THE HOMEOTIC UBX/EXD/DNA TERNARY COMPLEX
Descriptor: DNA (5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3'), PROTEIN (HOMEOBOX PROTEIN EXTRADENTICLE), ...
Authors:Passner, J.M, Ryoo, H.-D, Shen, L, Mann, R.S, Aggarwal, A.K.
Deposit date:1999-02-01
Release date:1999-04-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.
Nature, 397, 1999
1AU7
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BU of 1au7 by Molmil
PIT-1 MUTANT/DNA COMPLEX
Descriptor: CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1
Authors:Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K.
Deposit date:1997-09-12
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.
Genes Dev., 11, 1997
1U0J
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BU of 1u0j by Molmil
Crystal Structure of AAV2 Rep40-ADP complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA replication protein
Authors:James, J.A, Aggarwal, A.K, Linden, R.M, Escalante, C.R.
Deposit date:2004-07-13
Release date:2004-08-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of adeno-associated virus type 2 Rep40-ADP complex: Insight into nucleotide recognition and catalysis by superfamily 3 helicases
Proc.Natl.Acad.Sci.USA, 101, 2004
2FOK
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BU of 2fok by Molmil
STRUCTURE OF RESTRICTION ENDONUCLEASE FOKI
Descriptor: FOKI RESTRICTION ENDONUCLEASE
Authors:Wah, D.A, Bitinaite, J, Schildkraut, I, Aggarwal, A.K.
Deposit date:1998-03-30
Release date:1998-06-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of FokI has implications for DNA cleavage.
Proc.Natl.Acad.Sci.Usa, 95, 1998
1VRR
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BU of 1vrr by Molmil
Crystal structure of the restriction endonuclease BstYI complex with DNA
Descriptor: 5'-D(*TP*TP*AP*TP*AP*GP*AP*TP*CP*TP*AP*TP*AP*A)-3', BstYI
Authors:Townson, S.A, Samuelson, J.C, Xu, S.Y, Aggarwal, A.K.
Deposit date:2005-06-02
Release date:2005-06-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Implications for Switching Restriction Enzyme Specificities from the Structure of BstYI Bound to a BglII DNA Sequence.
Structure, 13, 2005
1ES8
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BU of 1es8 by Molmil
Crystal structure of free BglII
Descriptor: ACETIC ACID, RESTRICTION ENDONUCLEASE BGLII
Authors:Lukacs, C.M, Aggarwal, A.K.
Deposit date:2000-04-07
Release date:2001-01-17
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of free BglII reveals an unprecedented scissor-like motion for opening an endonuclease.
Nat.Struct.Biol., 8, 2001
7S0T
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BU of 7s0t by Molmil
Structure of DNA polymerase zeta with mismatched DNA
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
Authors:Malik, R, Ubarretxena, I.B, Aggarwal, A.K.
Deposit date:2021-08-31
Release date:2022-03-09
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Cryo-EM structure of translesion DNA synthesis polymerase zeta with a base pair mismatch.
Nat Commun, 13, 2022
7TW9
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BU of 7tw9 by Molmil
Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to Sinefungin
Descriptor: DI(HYDROXYETHYL)ETHER, ETHANOL, METHANOL, ...
Authors:Kottur, J, Aggarwal, A.K.
Deposit date:2022-02-06
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development.
Nat.Struct.Mol.Biol., 29, 2022
7TW7
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BU of 7tw7 by Molmil
Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SAM
Descriptor: S-ADENOSYLMETHIONINE, Transcription factor ETV6,Proofreading exoribonuclease nsp14 chimera, ZINC ION
Authors:Kottur, J, Aggarwal, A.K.
Deposit date:2022-02-06
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development.
Nat.Struct.Mol.Biol., 29, 2022
7TW8
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BU of 7tw8 by Molmil
Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SAH
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Transcription factor ETV6,Proofreading exoribonuclease nsp14 chimera, ZINC ION
Authors:Kottur, J, Aggarwal, A.K.
Deposit date:2022-02-06
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development.
Nat.Struct.Mol.Biol., 29, 2022
8FMH
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BU of 8fmh by Molmil
Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-dGAMP ligand (2 tetramers in the AU)
Descriptor: 3'2'-cGAMP, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K.
Deposit date:2022-12-23
Release date:2024-02-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 2024
8FMF
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BU of 8fmf by Molmil
Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (1 tetramer in the AU)
Descriptor: Cyclic (adenosine-(2'-5')-monophosphate-adenosine-(3'-5')-monophosphate, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K.
Deposit date:2022-12-23
Release date:2024-02-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 2024
8FMG
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BU of 8fmg by Molmil
Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (3 tetramers in the AU)
Descriptor: Cyclic (adenosine-(2'-5')-monophosphate-adenosine-(3'-5')-monophosphate, MAGNESIUM ION, SAVED domain-containing protein, ...
Authors:Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K.
Deposit date:2022-12-23
Release date:2024-02-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 2024
8FM1
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BU of 8fm1 by Molmil
Structure of CBASS Cap5 from Pseudomonas syringae in the absence of a ligand (apo form dimer)
Descriptor: SAVED domain-containing protein, ZINC ION
Authors:Rechkoblit, O, Kreitler, D.F, Aggarwal, A.K.
Deposit date:2022-12-22
Release date:2024-02-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.
Nat.Struct.Mol.Biol., 2024
8FRK
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BU of 8frk by Molmil
Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC8158
Descriptor: 5'-S-(4-{[(4'-chloro[1,1'-biphenyl]-3-yl)methyl]amino}butyl)-5'-thioadenosine, ETHANOL, POTASSIUM ION, ...
Authors:Kottur, J, Aggarwal, A.K.
Deposit date:2023-01-07
Release date:2023-07-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals.
Plos Pathog., 19, 2023

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